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Prevalence and risk factors of retinal arteriolar emboli: the Singapore Malay Eye Study.

Publication ,  Journal Article
Cheung, N; Lim, L; Wang, JJ; Islam, FMA; Mitchell, P; Saw, SM; Aung, T; Wong, TY
Published in: Am J Ophthalmol
October 2008

PURPOSE: To examine the prevalence and risk factors of retinal arteriolar emboli, a risk predictor of stroke, in an Asian population. DESIGN: Population-based cross-sectional study. METHODS: Retinal emboli were ascertained from retinal photographs obtained from both eyes of 3,265 Asian Malays, aged 40 to 80 years, according to a standardized protocol. Risk factors were assessed from detailed standardized interviews, clinical examinations, and laboratory investigations. RESULTS: The overall prevalence of retinal emboli was 0.6% (95% confidence interval [CI], 0.58 to 0.62). A finding of retinal emboli was strongly associated with increasing age (P = .005, for trend), but age-stratified prevalence rates were still lower than those reported from previous population-based studies of White persons. After adjusting for age and gender, the presence of retinal emboli was associated with cigarette smoking (odds ratio [OR], 5.96; 95% CI, 1.75 to 20.32), elevated total cholesterol (OR, 5.21; 95% CI, 1.93 to 12.82), low-density lipoprotein cholesterol (OR, 2.98; 95% CI, 1.20 to 7.39), and self-reported history of angina (OR, 5.67; 95% CI, 1.62 to 19.91). These associations remained significant in multivariate analysis with additional adjustment for other risk factors. CONCLUSIONS: Retinal emboli are less common in Asians than in similarly aged White persons, but are associated with similar cardiovascular risk factors.

Duke Scholars

Published In

Am J Ophthalmol

DOI

EISSN

1879-1891

Publication Date

October 2008

Volume

146

Issue

4

Start / End Page

620 / 624

Location

United States

Related Subject Headings

  • Stroke
  • Smoking
  • Singapore
  • Risk Factors
  • Retinal Diseases
  • Retinal Artery
  • Prevalence
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cheung, N., Lim, L., Wang, J. J., Islam, F. M. A., Mitchell, P., Saw, S. M., … Wong, T. Y. (2008). Prevalence and risk factors of retinal arteriolar emboli: the Singapore Malay Eye Study. Am J Ophthalmol, 146(4), 620–624. https://doi.org/10.1016/j.ajo.2008.05.033
Cheung, Ning, Lyndell Lim, Jie Jin Wang, FM Amirul Islam, Paul Mitchell, Seang Mei Saw, Tin Aung, and Tien Y. Wong. “Prevalence and risk factors of retinal arteriolar emboli: the Singapore Malay Eye Study.Am J Ophthalmol 146, no. 4 (October 2008): 620–24. https://doi.org/10.1016/j.ajo.2008.05.033.
Cheung N, Lim L, Wang JJ, Islam FMA, Mitchell P, Saw SM, et al. Prevalence and risk factors of retinal arteriolar emboli: the Singapore Malay Eye Study. Am J Ophthalmol. 2008 Oct;146(4):620–4.
Cheung, Ning, et al. “Prevalence and risk factors of retinal arteriolar emboli: the Singapore Malay Eye Study.Am J Ophthalmol, vol. 146, no. 4, Oct. 2008, pp. 620–24. Pubmed, doi:10.1016/j.ajo.2008.05.033.
Cheung N, Lim L, Wang JJ, Islam FMA, Mitchell P, Saw SM, Aung T, Wong TY. Prevalence and risk factors of retinal arteriolar emboli: the Singapore Malay Eye Study. Am J Ophthalmol. 2008 Oct;146(4):620–624.
Journal cover image

Published In

Am J Ophthalmol

DOI

EISSN

1879-1891

Publication Date

October 2008

Volume

146

Issue

4

Start / End Page

620 / 624

Location

United States

Related Subject Headings

  • Stroke
  • Smoking
  • Singapore
  • Risk Factors
  • Retinal Diseases
  • Retinal Artery
  • Prevalence
  • Ophthalmology & Optometry
  • Middle Aged
  • Male