Skip to main content

Are obesity and anthropometry risk factors for diabetic retinopathy? The diabetes management project.

Publication ,  Journal Article
Dirani, M; Xie, J; Fenwick, E; Benarous, R; Rees, G; Wong, TY; Lamoureux, EL
Published in: Invest Ophthalmol Vis Sci
June 22, 2011

PURPOSE: To investigate the relationship between anthropometric parameters and diabetic retinopathy (DR) in adults with diabetes. METHODS: Five hundred participants with diabetes were recruited prospectively from ophthalmology clinics in Melbourne, Australia. Each underwent an eye examination, anthropometric measurements, and standardized interview-administered questionnaires, and fasting blood glucose and serum lipids were analyzed. Two-field fundus photographs were taken and graded for DR. Height; weight; body mass index (BMI); waist, hip, neck, and head circumferences; and skinfold measurements were recorded. RESULTS: A total of 492 patients (325 men, 66.1%) aged between 26 and 90 years (median, 65) were included in the analysis: 171 (34.8%), 187 (38.0%), and 134 (27.2%) with no DR, nonproliferative DR (NPDR), and proliferative DR (PDR), respectively. After multiple adjustments, higher BMI (odds ratio [OR], 1.06; 95% confidence interval [CI],1.01-1.11; P = 0.02) was significantly associated with any DR. Obese people were 6.5 times more likely to have PDR than were those with normal weight (OR, 6.52; 95% CI, 1.49-28.6; P = 0.013). Neck circumference (OR, 1.05; 95% CI, 1.00-1.10; P = 0.03) and waist circumference (OR, 1.12; 95% CI, 1.03-1.22; P = 0.01) were significantly associated with any DR. BMI (OR, 1.04; 95% CI, 1.00-1.08; P = 0.04) and neck circumference (OR, 1.04 95% CI, 1.01-1.08; P = 0.04) were also positively associated with increasing severity levels of DR. CONCLUSIONS: Persons with diabetes with higher BMI and larger neck circumference are more likely to have DR and more severe stages of DR. These data suggest that obesity is an independent risk factor for DR.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

June 22, 2011

Volume

52

Issue

7

Start / End Page

4416 / 4421

Location

United States

Related Subject Headings

  • Victoria
  • Surveys and Questionnaires
  • Severity of Illness Index
  • Risk Factors
  • Prospective Studies
  • Prognosis
  • Ophthalmology & Optometry
  • Odds Ratio
  • Obesity
  • Middle Aged
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Dirani, M., Xie, J., Fenwick, E., Benarous, R., Rees, G., Wong, T. Y., & Lamoureux, E. L. (2011). Are obesity and anthropometry risk factors for diabetic retinopathy? The diabetes management project. Invest Ophthalmol Vis Sci, 52(7), 4416–4421. https://doi.org/10.1167/iovs.11-7208
Dirani, Mohamed, Jing Xie, Eva Fenwick, Rehab Benarous, Gwyneth Rees, Tien Yin Wong, and Ecosse L. Lamoureux. “Are obesity and anthropometry risk factors for diabetic retinopathy? The diabetes management project.Invest Ophthalmol Vis Sci 52, no. 7 (June 22, 2011): 4416–21. https://doi.org/10.1167/iovs.11-7208.
Dirani M, Xie J, Fenwick E, Benarous R, Rees G, Wong TY, et al. Are obesity and anthropometry risk factors for diabetic retinopathy? The diabetes management project. Invest Ophthalmol Vis Sci. 2011 Jun 22;52(7):4416–21.
Dirani, Mohamed, et al. “Are obesity and anthropometry risk factors for diabetic retinopathy? The diabetes management project.Invest Ophthalmol Vis Sci, vol. 52, no. 7, June 2011, pp. 4416–21. Pubmed, doi:10.1167/iovs.11-7208.
Dirani M, Xie J, Fenwick E, Benarous R, Rees G, Wong TY, Lamoureux EL. Are obesity and anthropometry risk factors for diabetic retinopathy? The diabetes management project. Invest Ophthalmol Vis Sci. 2011 Jun 22;52(7):4416–4421.

Published In

Invest Ophthalmol Vis Sci

DOI

EISSN

1552-5783

Publication Date

June 22, 2011

Volume

52

Issue

7

Start / End Page

4416 / 4421

Location

United States

Related Subject Headings

  • Victoria
  • Surveys and Questionnaires
  • Severity of Illness Index
  • Risk Factors
  • Prospective Studies
  • Prognosis
  • Ophthalmology & Optometry
  • Odds Ratio
  • Obesity
  • Middle Aged