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Ex-vivo liver perfusion for organ preservation: Recent advances in the field.

Publication ,  Journal Article
Barbas, AS; Goldaracena, N; Dib, MJ; Selzner, M
Published in: Transplant Rev (Orlando)
July 2016

Liver transplantation is the optimal treatment for end-stage liver disease but is limited by the severe shortage of donor organs. This shortage has prompted increased utilization of marginal grafts from DCD and extended criteria donors, which poorly tolerate cold storage in comparison to standard criteria grafts. Ex-vivo liver perfusion (EVLP) technology has emerged as a potential alternative to cold storage for organ preservation, but there is no consensus regarding the optimal temperature or conditions for EVLP. Herein, we review recent advances in both pre-clinical and clinical studies, organized by perfusion temperature (hypothermic, subnormothermic, normothermic).

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Published In

Transplant Rev (Orlando)

DOI

EISSN

1557-9816

Publication Date

July 2016

Volume

30

Issue

3

Start / End Page

154 / 160

Location

United States

Related Subject Headings

  • Tissue Donors
  • Surgery
  • Perfusion
  • Organ Preservation
  • Liver Transplantation
  • Liver
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

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Barbas, A. S., Goldaracena, N., Dib, M. J., & Selzner, M. (2016). Ex-vivo liver perfusion for organ preservation: Recent advances in the field. Transplant Rev (Orlando), 30(3), 154–160. https://doi.org/10.1016/j.trre.2016.03.002
Barbas, A. S., N. Goldaracena, M. J. Dib, and M. Selzner. “Ex-vivo liver perfusion for organ preservation: Recent advances in the field.Transplant Rev (Orlando) 30, no. 3 (July 2016): 154–60. https://doi.org/10.1016/j.trre.2016.03.002.
Barbas AS, Goldaracena N, Dib MJ, Selzner M. Ex-vivo liver perfusion for organ preservation: Recent advances in the field. Transplant Rev (Orlando). 2016 Jul;30(3):154–60.
Barbas, A. S., et al. “Ex-vivo liver perfusion for organ preservation: Recent advances in the field.Transplant Rev (Orlando), vol. 30, no. 3, July 2016, pp. 154–60. Pubmed, doi:10.1016/j.trre.2016.03.002.
Barbas AS, Goldaracena N, Dib MJ, Selzner M. Ex-vivo liver perfusion for organ preservation: Recent advances in the field. Transplant Rev (Orlando). 2016 Jul;30(3):154–160.
Journal cover image

Published In

Transplant Rev (Orlando)

DOI

EISSN

1557-9816

Publication Date

July 2016

Volume

30

Issue

3

Start / End Page

154 / 160

Location

United States

Related Subject Headings

  • Tissue Donors
  • Surgery
  • Perfusion
  • Organ Preservation
  • Liver Transplantation
  • Liver
  • Humans
  • 3202 Clinical sciences
  • 1103 Clinical Sciences