Matrix assisted pulsed laser evaporation of dexamethasone thin films
Publication
, Conference
Patz, TM; Doraiswamy, A; Narayan, RJ; Menegazzo, N; Kranz, C; Mizakoff, B; Zhong, Y; Bellamkonda, R; Modi, R; Chrisey, DB
Published in: Materials Research Society Symposium Proceedings
June 20, 2005
We have demonstrated deposition of dexamethasone thin films via matrix assisted pulsed laser evaporation (MAPLE). Infrared analysis revealed that dexamethasone thin films deposited by MAPLE and by drop casting had a similar absorbance spectra. AFM imaging of the MAPLE-deposited dexamethasone thin film revealed 2-10 μm punctuate ring-like structures. Deposited dexamethasone was tested for positive bioactivity by treating primary microglia cells with lipopolysacchride and measuring nitric oxide (NO) production. The successful deposition of dexamethasone thin films can be used on neural implants to prevent tissue injury and inflammatory response. © 2005 Materials Research Society.
Duke Scholars
Published In
Materials Research Society Symposium Proceedings
ISSN
0272-9172
Publication Date
June 20, 2005
Volume
845
Start / End Page
77 / 81
Citation
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ICMJE
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Patz, T. M., Doraiswamy, A., Narayan, R. J., Menegazzo, N., Kranz, C., Mizakoff, B., … Chrisey, D. B. (2005). Matrix assisted pulsed laser evaporation of dexamethasone thin films. In Materials Research Society Symposium Proceedings (Vol. 845, pp. 77–81).
Patz, T. M., A. Doraiswamy, R. J. Narayan, N. Menegazzo, C. Kranz, B. Mizakoff, Y. Zhong, R. Bellamkonda, R. Modi, and D. B. Chrisey. “Matrix assisted pulsed laser evaporation of dexamethasone thin films.” In Materials Research Society Symposium Proceedings, 845:77–81, 2005.
Patz TM, Doraiswamy A, Narayan RJ, Menegazzo N, Kranz C, Mizakoff B, et al. Matrix assisted pulsed laser evaporation of dexamethasone thin films. In: Materials Research Society Symposium Proceedings. 2005. p. 77–81.
Patz, T. M., et al. “Matrix assisted pulsed laser evaporation of dexamethasone thin films.” Materials Research Society Symposium Proceedings, vol. 845, 2005, pp. 77–81.
Patz TM, Doraiswamy A, Narayan RJ, Menegazzo N, Kranz C, Mizakoff B, Zhong Y, Bellamkonda R, Modi R, Chrisey DB. Matrix assisted pulsed laser evaporation of dexamethasone thin films. Materials Research Society Symposium Proceedings. 2005. p. 77–81.
Published In
Materials Research Society Symposium Proceedings
ISSN
0272-9172
Publication Date
June 20, 2005
Volume
845
Start / End Page
77 / 81