A tissue engineering approach in understanding regenerative failure in the central nervous system
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Gilbert, RJ; Bellamkonda, RV
Published in: Transactions - 7th World Biomaterials Congress
December 1, 2004
A tissue engineering approach consisting of a three-dimensional (3D) culture system where immobilized glycosaminoglycan (GAG) is presented to dorsal root ganglion (DRG) neurons was investigated. CS-B, CS-C and bovine nasal septum aggrecan were immobilized onto 1% agarose hydrogel, using photocrosslinking chemistry. Neurite outgrowth was significantly reduced when aggrecan was immobilized onto the agarose system. The results indicate that soluble 6-sulfated GAG (CS-C) show significant inhibition when compared to unmodified agarose.
Duke Scholars
Published In
Transactions - 7th World Biomaterials Congress
ISBN
9781877040191
Publication Date
December 1, 2004
Start / End Page
731
Citation
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Gilbert, R. J., & Bellamkonda, R. V. (2004). A tissue engineering approach in understanding regenerative failure in the central nervous system. In Transactions - 7th World Biomaterials Congress (p. 731).
Gilbert, R. J., and R. V. Bellamkonda. “A tissue engineering approach in understanding regenerative failure in the central nervous system.” In Transactions - 7th World Biomaterials Congress, 731, 2004.
Gilbert RJ, Bellamkonda RV. A tissue engineering approach in understanding regenerative failure in the central nervous system. In: Transactions - 7th World Biomaterials Congress. 2004. p. 731.
Gilbert, R. J., and R. V. Bellamkonda. “A tissue engineering approach in understanding regenerative failure in the central nervous system.” Transactions - 7th World Biomaterials Congress, 2004, p. 731.
Gilbert RJ, Bellamkonda RV. A tissue engineering approach in understanding regenerative failure in the central nervous system. Transactions - 7th World Biomaterials Congress. 2004. p. 731.
Published In
Transactions - 7th World Biomaterials Congress
ISBN
9781877040191
Publication Date
December 1, 2004
Start / End Page
731