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Titin and nebulin content in human skeletal muscle following eccentric resistance exercise.

Publication ,  Journal Article
Trappe, TA; Carrithers, JA; White, F; Lambert, CP; Evans, WJ; Dennis, RA
Published in: Muscle Nerve
February 2002

We measured titin and nebulin content in muscle biopsies from the vastus lateralis before and 24 h after one bout of high-intensity eccentric knee extensor resistance exercise in seven men (26 +/- 3 years). Titin and nebulin content were significantly (P < 0.05) reduced after exercise by 30 and 15%, respectively. These results suggest that the structural components of the myofibrillar apparatus are degraded following high-intensity eccentric resistance exercise in humans. Loss of these proteins may have important implications for the mechanisms regulating the adaptive response of skeletal muscle to resistance exercise.

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Published In

Muscle Nerve

DOI

ISSN

0148-639X

Publication Date

February 2002

Volume

25

Issue

2

Start / End Page

289 / 292

Location

United States

Related Subject Headings

  • Weight Lifting
  • Protein Kinases
  • Neurology & Neurosurgery
  • Muscle, Skeletal
  • Muscle Proteins
  • Male
  • Humans
  • Connectin
  • Adult
  • 32 Biomedical and clinical sciences
 

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Trappe, T. A., Carrithers, J. A., White, F., Lambert, C. P., Evans, W. J., & Dennis, R. A. (2002). Titin and nebulin content in human skeletal muscle following eccentric resistance exercise. Muscle Nerve, 25(2), 289–292. https://doi.org/10.1002/mus.10037
Trappe, Todd A., John A. Carrithers, Faber White, Charles P. Lambert, William J. Evans, and Richard A. Dennis. “Titin and nebulin content in human skeletal muscle following eccentric resistance exercise.Muscle Nerve 25, no. 2 (February 2002): 289–92. https://doi.org/10.1002/mus.10037.
Trappe TA, Carrithers JA, White F, Lambert CP, Evans WJ, Dennis RA. Titin and nebulin content in human skeletal muscle following eccentric resistance exercise. Muscle Nerve. 2002 Feb;25(2):289–92.
Trappe, Todd A., et al. “Titin and nebulin content in human skeletal muscle following eccentric resistance exercise.Muscle Nerve, vol. 25, no. 2, Feb. 2002, pp. 289–92. Pubmed, doi:10.1002/mus.10037.
Trappe TA, Carrithers JA, White F, Lambert CP, Evans WJ, Dennis RA. Titin and nebulin content in human skeletal muscle following eccentric resistance exercise. Muscle Nerve. 2002 Feb;25(2):289–292.
Journal cover image

Published In

Muscle Nerve

DOI

ISSN

0148-639X

Publication Date

February 2002

Volume

25

Issue

2

Start / End Page

289 / 292

Location

United States

Related Subject Headings

  • Weight Lifting
  • Protein Kinases
  • Neurology & Neurosurgery
  • Muscle, Skeletal
  • Muscle Proteins
  • Male
  • Humans
  • Connectin
  • Adult
  • 32 Biomedical and clinical sciences