Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART.
Publication
, Journal Article
Evans, WJ; Kotler, DP; Staszewski, S; Griffin, GE; Isgaard, J; Gertner, JM; O'Brien, F; Svanberg, E
Published in: AIDS Read
June 2005
Over 700 patients with HIV-associated wasting while receiving HAART were randomly assigned to double-blind treatment for 12 weeks with recombinant human growth hormone (rhGH) daily or on alternate days, or to placebo. Maximum exercise intensity increased by a median of 2.35kJ in the alternate-days group and 2.60 kJ in the daily group but decreased by 0.25kJ in the placebo group. The median difference between the daily and placebo groups was 2.85 kJ (P < .0001). These improvements suggest that rhGH treatment may enable patients with wasting to perform activities of daily living that would be exhausting without rhGH treatment.
Duke Scholars
Published In
AIDS Read
ISSN
1053-0894
Publication Date
June 2005
Volume
15
Issue
6
Start / End Page
301 / 314
Location
United States
Related Subject Headings
- Virology
- Treatment Outcome
- Risk Assessment
- Reference Values
- Recombinant Proteins
- Probability
- Middle Aged
- Male
- Humans
- Human Growth Hormone
Citation
APA
Chicago
ICMJE
MLA
NLM
Evans, W. J., Kotler, D. P., Staszewski, S., Griffin, G. E., Isgaard, J., Gertner, J. M., … Svanberg, E. (2005). Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART. AIDS Read, 15(6), 301–314.
Evans, William J., Donald P. Kotler, Schlomo Staszewski, George E. Griffin, Jorgen Isgaard, Joseph M. Gertner, Fanny O’Brien, and Elisabeth Svanberg. “Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART.” AIDS Read 15, no. 6 (June 2005): 301–14.
Evans WJ, Kotler DP, Staszewski S, Griffin GE, Isgaard J, Gertner JM, et al. Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART. AIDS Read. 2005 Jun;15(6):301–14.
Evans, William J., et al. “Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART.” AIDS Read, vol. 15, no. 6, June 2005, pp. 301–14.
Evans WJ, Kotler DP, Staszewski S, Griffin GE, Isgaard J, Gertner JM, O’Brien F, Svanberg E. Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART. AIDS Read. 2005 Jun;15(6):301–314.
Published In
AIDS Read
ISSN
1053-0894
Publication Date
June 2005
Volume
15
Issue
6
Start / End Page
301 / 314
Location
United States
Related Subject Headings
- Virology
- Treatment Outcome
- Risk Assessment
- Reference Values
- Recombinant Proteins
- Probability
- Middle Aged
- Male
- Humans
- Human Growth Hormone