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Disease drivers of aging.

Publication ,  Journal Article
Hodes, RJ; Sierra, F; Austad, SN; Epel, E; Neigh, GN; Erlandson, KM; Schafer, MJ; LeBrasseur, NK; Wiley, C; Campisi, J; Sehl, ME; Scalia, R ...
Published in: Ann N Y Acad Sci
December 2016

It has long been known that aging, at both the cellular and organismal levels, contributes to the development and progression of the pathology of many chronic diseases. However, much less research has examined the inverse relationship-the contribution of chronic diseases and their treatments to the progression of aging-related phenotypes. Here, we discuss the impact of three chronic diseases (cancer, HIV/AIDS, and diabetes) and their treatments on aging, putative mechanisms by which these effects are mediated, and the open questions and future research directions required to understand the relationships between these diseases and aging.

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Published In

Ann N Y Acad Sci

DOI

EISSN

1749-6632

Publication Date

December 2016

Volume

1386

Issue

1

Start / End Page

45 / 68

Location

United States

Related Subject Headings

  • Neoplasms
  • Humans
  • General Science & Technology
  • Diabetes Mellitus
  • Chronic Disease
  • Aging
  • Acquired Immunodeficiency Syndrome
 

Citation

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Hodes, R. J., Sierra, F., Austad, S. N., Epel, E., Neigh, G. N., Erlandson, K. M., … Hunt, P. W. (2016). Disease drivers of aging. Ann N Y Acad Sci, 1386(1), 45–68. https://doi.org/10.1111/nyas.13299
Hodes, Richard J., Felipe Sierra, Steven N. Austad, Elissa Epel, Gretchen N. Neigh, Kristine M. Erlandson, Marissa J. Schafer, et al. “Disease drivers of aging.Ann N Y Acad Sci 1386, no. 1 (December 2016): 45–68. https://doi.org/10.1111/nyas.13299.
Hodes RJ, Sierra F, Austad SN, Epel E, Neigh GN, Erlandson KM, et al. Disease drivers of aging. Ann N Y Acad Sci. 2016 Dec;1386(1):45–68.
Hodes, Richard J., et al. “Disease drivers of aging.Ann N Y Acad Sci, vol. 1386, no. 1, Dec. 2016, pp. 45–68. Pubmed, doi:10.1111/nyas.13299.
Hodes RJ, Sierra F, Austad SN, Epel E, Neigh GN, Erlandson KM, Schafer MJ, LeBrasseur NK, Wiley C, Campisi J, Sehl ME, Scalia R, Eguchi S, Kasinath BS, Halter JB, Cohen HJ, Demark-Wahnefried W, Ahles TA, Barzilai N, Hurria A, Hunt PW. Disease drivers of aging. Ann N Y Acad Sci. 2016 Dec;1386(1):45–68.
Journal cover image

Published In

Ann N Y Acad Sci

DOI

EISSN

1749-6632

Publication Date

December 2016

Volume

1386

Issue

1

Start / End Page

45 / 68

Location

United States

Related Subject Headings

  • Neoplasms
  • Humans
  • General Science & Technology
  • Diabetes Mellitus
  • Chronic Disease
  • Aging
  • Acquired Immunodeficiency Syndrome