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Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase.

Publication ,  Journal Article
Phillíps, CL; Ullman, B; Brennan, RG
Published in: Proteins
August 1996

Adenine phosphoribosyltransferase from the protozoan parasite Leishmania donovani has been crystallized in the presence of the substrate Mg(2+)-alpha-D-5-phosphoribosyl-1-pyrophosphate (PRPP) or the product adenosine-5-monophosphate, as well as in the absence of ligand. These crystals belong to the space group P6(1)22 or its enantiomorph P6(5)22, with unit cell dimensions of a = b = 64.0 A, c = 240.5 A, alpha = beta = 90 degrees, and gamma = 120 degrees. The crystals diffract to 1.9 A.

Duke Scholars

Published In

Proteins

DOI

ISSN

0887-3585

Publication Date

August 1996

Volume

25

Issue

4

Start / End Page

510 / 513

Location

United States

Related Subject Headings

  • X-Ray Diffraction
  • Stereoisomerism
  • Leishmania donovani
  • Crystallization
  • Bioinformatics
  • Animals
  • Adenine Phosphoribosyltransferase
  • 49 Mathematical sciences
  • 31 Biological sciences
  • 08 Information and Computing Sciences
 

Citation

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Phillíps, C. L., Ullman, B., & Brennan, R. G. (1996). Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase. Proteins, 25(4), 510–513. https://doi.org/10.1002/prot.11
Phillíps, C. L., B. Ullman, and R. G. Brennan. “Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase.Proteins 25, no. 4 (August 1996): 510–13. https://doi.org/10.1002/prot.11.
Phillíps CL, Ullman B, Brennan RG. Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase. Proteins. 1996 Aug;25(4):510–3.
Phillíps, C. L., et al. “Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase.Proteins, vol. 25, no. 4, Aug. 1996, pp. 510–13. Pubmed, doi:10.1002/prot.11.
Phillíps CL, Ullman B, Brennan RG. Crystallization of the purine salvage enzyme adenine phosphoribosyltransferase. Proteins. 1996 Aug;25(4):510–513.
Journal cover image

Published In

Proteins

DOI

ISSN

0887-3585

Publication Date

August 1996

Volume

25

Issue

4

Start / End Page

510 / 513

Location

United States

Related Subject Headings

  • X-Ray Diffraction
  • Stereoisomerism
  • Leishmania donovani
  • Crystallization
  • Bioinformatics
  • Animals
  • Adenine Phosphoribosyltransferase
  • 49 Mathematical sciences
  • 31 Biological sciences
  • 08 Information and Computing Sciences