PEG-bovine hemoglobin: safety in a canine dehydrated hypovolemic-hemorrhagic shock model.
Publication
, Journal Article
Nho, K; Glower, D; Bredehoeft, S; Shankar, H; Shorr, R; Abuchowski, A
Published in: Biomater Artif Cells Immobilization Biotechnol
1992
An initial evaluation of PEG-bHb was performed using a modified hypovolemic shock model. PEG-bHb had a substantially longer intravascular half-life than native Hb and no measurable hemoglobinuria was observed in the canine. PEG-bHb allowed successful resuscitation with an oxygen carrying capacity of 14-22% over that of lactated Ringer's solution.
Duke Scholars
Published In
Biomater Artif Cells Immobilization Biotechnol
DOI
ISSN
1055-7172
Publication Date
1992
Volume
20
Issue
2-4
Start / End Page
511 / 524
Location
United States
Related Subject Headings
- Shock, Hemorrhagic
- Shock
- Safety
- Ringer's Lactate
- Resuscitation
- Polyethylene Glycols
- Isotonic Solutions
- Hemoglobins
- Half-Life
- Dogs
Citation
APA
Chicago
ICMJE
MLA
NLM
Nho, K., Glower, D., Bredehoeft, S., Shankar, H., Shorr, R., & Abuchowski, A. (1992). PEG-bovine hemoglobin: safety in a canine dehydrated hypovolemic-hemorrhagic shock model. Biomater Artif Cells Immobilization Biotechnol, 20(2–4), 511–524. https://doi.org/10.3109/10731199209119677
Nho, K., D. Glower, S. Bredehoeft, H. Shankar, R. Shorr, and A. Abuchowski. “PEG-bovine hemoglobin: safety in a canine dehydrated hypovolemic-hemorrhagic shock model.” Biomater Artif Cells Immobilization Biotechnol 20, no. 2–4 (1992): 511–24. https://doi.org/10.3109/10731199209119677.
Nho K, Glower D, Bredehoeft S, Shankar H, Shorr R, Abuchowski A. PEG-bovine hemoglobin: safety in a canine dehydrated hypovolemic-hemorrhagic shock model. Biomater Artif Cells Immobilization Biotechnol. 1992;20(2–4):511–24.
Nho, K., et al. “PEG-bovine hemoglobin: safety in a canine dehydrated hypovolemic-hemorrhagic shock model.” Biomater Artif Cells Immobilization Biotechnol, vol. 20, no. 2–4, 1992, pp. 511–24. Pubmed, doi:10.3109/10731199209119677.
Nho K, Glower D, Bredehoeft S, Shankar H, Shorr R, Abuchowski A. PEG-bovine hemoglobin: safety in a canine dehydrated hypovolemic-hemorrhagic shock model. Biomater Artif Cells Immobilization Biotechnol. 1992;20(2–4):511–524.
Published In
Biomater Artif Cells Immobilization Biotechnol
DOI
ISSN
1055-7172
Publication Date
1992
Volume
20
Issue
2-4
Start / End Page
511 / 524
Location
United States
Related Subject Headings
- Shock, Hemorrhagic
- Shock
- Safety
- Ringer's Lactate
- Resuscitation
- Polyethylene Glycols
- Isotonic Solutions
- Hemoglobins
- Half-Life
- Dogs