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The effect of medical therapy on IOP control in Ghana.

Publication ,  Journal Article
Gyasi, ME; Andrew, F; Adjuik, M; Kesse, E; Kodjo, RA; Herndon, L
Published in: Ghana Med J
September 2014

BACKGROUND: To investigate IOP control following twelve months of continuous medical therapy in Ghana. METHODS: This retrospective case series included 163 glaucoma patients diagnosed at a referral eye center between 1996 and 2006. Information collected included age, gender, IOP at presentation, six months and one year post treatment and types of anti-glaucoma medications prescribed. Optimal IOP control was defined according to results from the Advanced Glaucoma Intervention Study (AGIS), which demonstrated arrest of visual field progression in patients with IOP < 18 mmHg at all visitations: Level 1 (post-treatment IOP ≤ 21 mmHg); Level 2 (≤ 18 mmHg) and level 3 (≤ 16 mmHg). The principal outcome measure was the achievement of IOP <18 mmHg at six months and twelve month visitations. RESULTS: One hundred sixty three patients were analyzed. These included 68 males (41.7%) and 95 females (58.3%). The mean age was 57±16 (median 59 years; range 7 - 95 years). There was no significant difference in age (p=0.35) or mean IOP (p=0.08) between genders. The mean pre-treated IOP of 31.9±8.9 mmHg significantly decreased to 21.3±6.6 mmHg at 6 months (p=0.001), with 57.4% of eyes at Level 1 IOP control, 25.3% at Level 2 and 15.4% at Level 3 and decreased further at 12 months to 20.7±6.9 mmHg (p=0.48) with 69.7% of eyes at Level 1, 34.4% at Level 2, and 12.4% at Level 3. CONCLUSIONS: Current medical regimen is insufficient to reduce IOP to target levels as defined in the Advanced Glaucoma Intervention Study.

Duke Scholars

Published In

Ghana Med J

DOI

EISSN

2616-163X

Publication Date

September 2014

Volume

48

Issue

3

Start / End Page

148 / 152

Location

Ghana

Related Subject Headings

  • Young Adult
  • Time Factors
  • Retrospective Studies
  • Prostaglandins
  • Parasympathomimetics
  • Middle Aged
  • Male
  • Intraocular Pressure
  • Humans
  • Glaucoma, Open-Angle
 

Citation

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Gyasi, M. E., Andrew, F., Adjuik, M., Kesse, E., Kodjo, R. A., & Herndon, L. (2014). The effect of medical therapy on IOP control in Ghana. Ghana Med J, 48(3), 148–152. https://doi.org/10.4314/gmj.v48i3.5
Gyasi, M. E., F. Andrew, M. Adjuik, E. Kesse, R. A. Kodjo, and L. Herndon. “The effect of medical therapy on IOP control in Ghana.Ghana Med J 48, no. 3 (September 2014): 148–52. https://doi.org/10.4314/gmj.v48i3.5.
Gyasi ME, Andrew F, Adjuik M, Kesse E, Kodjo RA, Herndon L. The effect of medical therapy on IOP control in Ghana. Ghana Med J. 2014 Sep;48(3):148–52.
Gyasi, M. E., et al. “The effect of medical therapy on IOP control in Ghana.Ghana Med J, vol. 48, no. 3, Sept. 2014, pp. 148–52. Pubmed, doi:10.4314/gmj.v48i3.5.
Gyasi ME, Andrew F, Adjuik M, Kesse E, Kodjo RA, Herndon L. The effect of medical therapy on IOP control in Ghana. Ghana Med J. 2014 Sep;48(3):148–152.

Published In

Ghana Med J

DOI

EISSN

2616-163X

Publication Date

September 2014

Volume

48

Issue

3

Start / End Page

148 / 152

Location

Ghana

Related Subject Headings

  • Young Adult
  • Time Factors
  • Retrospective Studies
  • Prostaglandins
  • Parasympathomimetics
  • Middle Aged
  • Male
  • Intraocular Pressure
  • Humans
  • Glaucoma, Open-Angle