In vivo acylation of triglycerides and phosphoglycerides of liver subcellular fractions with palmitate-1-14C in rats fed vitamin A.

Incorporation of palmitate-1-14C into liver and its mitochondrial, and microsomal triglycerides and phosphoglycerides of rats fed 100000 I.U. of vitamin A for two days has been studied. Feeding of vitamin A significantly increased triglycerides in liver and its mitochondrial, microsomal and supernatant fractions as compared to the controls. A significant increase in total phospholipids and phosphatidyl choline was noted in liver mitochondrial and microsomal fractions of vitamin A fed rats. The incorporation of palmitate-1-14C (counts/min/liver) into triglycerides of liver mitochondrial, microsomal and supernatant fractions of vitamin A fed rats was significantly higher, whereas in phosphatidyl ethanolamine and phosphatidyl choline it was not significantly different from the controls.

Duke Scholars

Author Uma Kant Misra Pathology