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Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition

Developing the Value Proposition for Personalized Medicine

Publication ,  Chapter
Reed, SD; Faulkner, E; Veenstra, DL
January 1, 2017

Standard methodological approaches have successfully been applied to evaluate the cost-effectiveness of numerous personalized medicine tests, particularly for companion diagnostics developed in the context of a clinical trial. However, disagreement has emerged about the extent to which existing methods can characterize the value of personalized medicine. This chapter provides an overview of cost-effectiveness analysis and the factors determining the value of personalized medicine. The authors identify limitations of the traditional cost-effectiveness analysis framework and methodological issues that will arise with increasing use of multiple "omics" profiles to guide individualized selection of treatments.

Duke Scholars

DOI

ISBN

9780128006818

Publication Date

January 1, 2017

Start / End Page

327 / 342
 

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Reed, S. D., Faulkner, E., & Veenstra, D. L. (2017). Developing the Value Proposition for Personalized Medicine. In Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition (pp. 327–342). https://doi.org/10.1016/B978-0-12-800681-8.00022-0
Reed, S. D., E. Faulkner, and D. L. Veenstra. “Developing the Value Proposition for Personalized Medicine.” In Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition, 327–42, 2017. https://doi.org/10.1016/B978-0-12-800681-8.00022-0.
Reed SD, Faulkner E, Veenstra DL. Developing the Value Proposition for Personalized Medicine. In: Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition. 2017. p. 327–42.
Reed, S. D., et al. “Developing the Value Proposition for Personalized Medicine.” Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition, 2017, pp. 327–42. Scopus, doi:10.1016/B978-0-12-800681-8.00022-0.
Reed SD, Faulkner E, Veenstra DL. Developing the Value Proposition for Personalized Medicine. Genomic and Precision Medicine: Foundations, Translation, and Implementation: Third Edition. 2017. p. 327–342.
Journal cover image

DOI

ISBN

9780128006818

Publication Date

January 1, 2017

Start / End Page

327 / 342