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A pilot study of the use of biocide-impregnated gauze as an adjunct to wound care in a burn population.

Publication ,  Journal Article
Wibbenmeyer, L; Williams, I; Liao, J; Heard, J; Kealey, GP; Miller, R
Published in: J Burn Care Res
2012

The aim of this study was to evaluate the use of a polyhexamethylene biguanide biocide-impregnated gauze (Kerlix™ AMD gauze dressing, Covidien d/b/a Tyco Healthcare Group LP) as an adjuvant to routine burn care and its impact on the incidence of hospital-associated infections in burn population. One hundred eight burn patients admitted to the Burn Treatment Center were prospectively enrolled from August 2008 to June 2009 and matched 1:2 with historic controls who were admitted from March 2006 to July 2008. Clinical care remained otherwise unchanged; however, several hospital initiatives (the national surgical improvement project, the surgical care improvement project, and a central venous line bundle) were initiated before and during the study. There were significantly less infections in the study population (18.52% of case patients vs 28.70% of control patients had infections, P = .047). Although there was a decrease in each infection subtype analyzed, a statistically significant reduction was only reached for pneumonias (1.85% in cases vs 5.86 in controls, P = .042). Implementation of polyhexamethylene biguanide biocide-impregnated gauze was temporally correlated with a significant decrease in healthcare-associated infections in burn population. As there was no corresponding decrease in wound infections, the impact of the gauze on healthcare-associated infections, if any, cannot be conclusively determined by this study. A larger prospective study powered to detect a decrease in wound-related infections is warranted.

Duke Scholars

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Published In

J Burn Care Res

DOI

EISSN

1559-0488

Publication Date

2012

Volume

33

Issue

3

Start / End Page

358 / 363

Location

England

Related Subject Headings

  • Young Adult
  • Wound Infection
  • Wound Healing
  • Treatment Outcome
  • Risk Assessment
  • Reference Values
  • Prospective Studies
  • Pilot Projects
  • Middle Aged
  • Male
 

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Wibbenmeyer, L., Williams, I., Liao, J., Heard, J., Kealey, G. P., & Miller, R. (2012). A pilot study of the use of biocide-impregnated gauze as an adjunct to wound care in a burn population. J Burn Care Res, 33(3), 358–363. https://doi.org/10.1097/BCR.0b013e31823746d2
Wibbenmeyer, Lucy, Ingrid Williams, Junlin Liao, Jason Heard, Gerald Patrick Kealey, and Rachel Miller. “A pilot study of the use of biocide-impregnated gauze as an adjunct to wound care in a burn population.J Burn Care Res 33, no. 3 (2012): 358–63. https://doi.org/10.1097/BCR.0b013e31823746d2.
Wibbenmeyer L, Williams I, Liao J, Heard J, Kealey GP, Miller R. A pilot study of the use of biocide-impregnated gauze as an adjunct to wound care in a burn population. J Burn Care Res. 2012;33(3):358–63.
Wibbenmeyer, Lucy, et al. “A pilot study of the use of biocide-impregnated gauze as an adjunct to wound care in a burn population.J Burn Care Res, vol. 33, no. 3, 2012, pp. 358–63. Pubmed, doi:10.1097/BCR.0b013e31823746d2.
Wibbenmeyer L, Williams I, Liao J, Heard J, Kealey GP, Miller R. A pilot study of the use of biocide-impregnated gauze as an adjunct to wound care in a burn population. J Burn Care Res. 2012;33(3):358–363.
Journal cover image

Published In

J Burn Care Res

DOI

EISSN

1559-0488

Publication Date

2012

Volume

33

Issue

3

Start / End Page

358 / 363

Location

England

Related Subject Headings

  • Young Adult
  • Wound Infection
  • Wound Healing
  • Treatment Outcome
  • Risk Assessment
  • Reference Values
  • Prospective Studies
  • Pilot Projects
  • Middle Aged
  • Male