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Assembly of type C oncornaviruses: a model.

Publication ,  Journal Article
Bolognesi, DP; Montelaro, RC; Frank, H; Schäfer, W
Published in: Science
January 13, 1978

The salient features of this model for oncornavirus assembly are that uncleaved precursor molecules to the internal virus polypeptides possess specific recognition sites both for viral envelope constituents already inserted in the cell membrane and for the viral RNA. After orderly alignment of these components at the budding site, virus maturation proceeds through specific proteolytic cleavage of the precursor components and association of the resultant molecules into the characteristic type C virion substructures revealed by electron microscopy.

Duke Scholars

Published In

Science

DOI

ISSN

0036-8075

Publication Date

January 13, 1978

Volume

199

Issue

4325

Start / End Page

183 / 186

Location

United States

Related Subject Headings

  • Virus Replication
  • Viral Proteins
  • Retroviridae
  • Protein Precursors
  • Models, Biological
  • Glycoproteins
  • General Science & Technology
  • Cell Membrane
 

Citation

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MLA
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Bolognesi, D. P., Montelaro, R. C., Frank, H., & Schäfer, W. (1978). Assembly of type C oncornaviruses: a model. Science, 199(4325), 183–186. https://doi.org/10.1126/science.202022
Bolognesi, D. P., R. C. Montelaro, H. Frank, and W. Schäfer. “Assembly of type C oncornaviruses: a model.Science 199, no. 4325 (January 13, 1978): 183–86. https://doi.org/10.1126/science.202022.
Bolognesi DP, Montelaro RC, Frank H, Schäfer W. Assembly of type C oncornaviruses: a model. Science. 1978 Jan 13;199(4325):183–6.
Bolognesi, D. P., et al. “Assembly of type C oncornaviruses: a model.Science, vol. 199, no. 4325, Jan. 1978, pp. 183–86. Pubmed, doi:10.1126/science.202022.
Bolognesi DP, Montelaro RC, Frank H, Schäfer W. Assembly of type C oncornaviruses: a model. Science. 1978 Jan 13;199(4325):183–186.
Journal cover image

Published In

Science

DOI

ISSN

0036-8075

Publication Date

January 13, 1978

Volume

199

Issue

4325

Start / End Page

183 / 186

Location

United States

Related Subject Headings

  • Virus Replication
  • Viral Proteins
  • Retroviridae
  • Protein Precursors
  • Models, Biological
  • Glycoproteins
  • General Science & Technology
  • Cell Membrane