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Properties of mouse leukemia viruses. XIV. Prevention of spontaneous AKR leukemia by treatment with group-specific antibody against the major virus gp71 glycoprotein.

Publication ,  Journal Article
Schäfer, W; Schwarz, H; Thiel, HJ; Fischinger, PJ; Bolognesi, DP
Published in: Virology
November 1977

Treatment of AKR mice early in life with potent goat antibody to the major virus glycoprotein (gp71) of Friend leukemia virus resulted in marked prevention of fatal AKR disease. Even better protection could be achieved when, in addition, the mothers were treated with the same antibody at least 3-4 days antepartum. From these preliminary observations, we conclude that antibody specific for the broadly cross-reacting determinants of this virus glycoprotein can control development of spontaneous leukemias mediated by replicating endogenous viruses.

Duke Scholars

Published In

Virology

DOI

ISSN

0042-6822

Publication Date

November 1977

Volume

83

Issue

1

Start / End Page

207 / 210

Location

United States

Related Subject Headings

  • Virology
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 30 Agricultural, veterinary and food sciences
  • 11 Medical and Health Sciences
  • 07 Agricultural and Veterinary Sciences
  • 06 Biological Sciences
 

Citation

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Schäfer, W., Schwarz, H., Thiel, H. J., Fischinger, P. J., & Bolognesi, D. P. (1977). Properties of mouse leukemia viruses. XIV. Prevention of spontaneous AKR leukemia by treatment with group-specific antibody against the major virus gp71 glycoprotein. Virology, 83(1), 207–210. https://doi.org/10.1016/0042-6822(77)90224-0
Schäfer, W., H. Schwarz, H. J. Thiel, P. J. Fischinger, and D. P. Bolognesi. “Properties of mouse leukemia viruses. XIV. Prevention of spontaneous AKR leukemia by treatment with group-specific antibody against the major virus gp71 glycoprotein.Virology 83, no. 1 (November 1977): 207–10. https://doi.org/10.1016/0042-6822(77)90224-0.
Schäfer, W., et al. “Properties of mouse leukemia viruses. XIV. Prevention of spontaneous AKR leukemia by treatment with group-specific antibody against the major virus gp71 glycoprotein.Virology, vol. 83, no. 1, Nov. 1977, pp. 207–10. Pubmed, doi:10.1016/0042-6822(77)90224-0.
Journal cover image

Published In

Virology

DOI

ISSN

0042-6822

Publication Date

November 1977

Volume

83

Issue

1

Start / End Page

207 / 210

Location

United States

Related Subject Headings

  • Virology
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 30 Agricultural, veterinary and food sciences
  • 11 Medical and Health Sciences
  • 07 Agricultural and Veterinary Sciences
  • 06 Biological Sciences