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Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes.

Publication ,  Journal Article
Davy, BM; Winett, RA; Savla, J; Marinik, EL; Baugh, ME; Flack, KD; Halliday, TM; Kelleher, SA; Winett, SG; Williams, DM; Boshra, S
Published in: PLoS One
2017

OBJECTIVE: To determine whether a social cognitive theory (SCT)-based intervention improves resistance training (RT) maintenance and strength, and reduces prediabetes prevalence. RESEARCH DESIGN AND METHODS: Sedentary, overweight/obese (BMI: 25-39.9 kg/m2) adults aged 50-69 (N = 170) with prediabetes participated in the 15-month trial. Participants completed a supervised 3-month RT (2×/wk) phase and were randomly assigned (N = 159) to one of two 6-month maintenance conditions: SCT or standard care. Participants continued RT at a self-selected facility. The final 6-month period involved no contact. Assessments occurred at baseline and months 3, 9, and 15. The SCT faded-contact intervention consisted of nine tailored transition (i.e., supervised training to training alone) and nine follow-up sessions. Standard care involved six generic follow-up sessions. Primary outcomes were prevalence of normoglycemia and muscular strength. RESULTS: The retention rate was 76%. Four serious adverse events were reported. After 3 months of RT, 34% of participants were no longer prediabetic. This prevalence of normoglycemia was maintained through month 15 (30%), with no group difference. There was an 18% increase in the odds of being normoglycemic for each % increase in fat-free mass. Increases in muscular strength were evident at month 3 and maintained through month 15 (P<0.001), which represented improvements of 21% and 14% for chest and leg press, respectively. Results did not demonstrate a greater reduction in prediabetes prevalence in the SCT condition. CONCLUSIONS: Resistance training is an effective, maintainable strategy for reducing prediabetes prevalence and increasing muscular strength. Future research which promotes RT initiation and maintenance in clinical and community settings is warranted. TRIAL REGISTRATION: ClinicalTrials.gov NCT01112709.

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Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2017

Volume

12

Issue

2

Start / End Page

e0172610

Location

United States

Related Subject Headings

  • Sedentary Behavior
  • Resistance Training
  • Prediabetic State
  • Overweight
  • Muscle Strength
  • Middle Aged
  • Male
  • Humans
  • General Science & Technology
  • Female
 

Citation

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Chicago
ICMJE
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Davy, B. M., Winett, R. A., Savla, J., Marinik, E. L., Baugh, M. E., Flack, K. D., … Boshra, S. (2017). Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes. PLoS One, 12(2), e0172610. https://doi.org/10.1371/journal.pone.0172610
Davy, Brenda M., Richard A. Winett, Jyoti Savla, Elaina L. Marinik, Mary Elizabeth Baugh, Kyle D. Flack, Tanya M. Halliday, et al. “Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes.PLoS One 12, no. 2 (2017): e0172610. https://doi.org/10.1371/journal.pone.0172610.
Davy BM, Winett RA, Savla J, Marinik EL, Baugh ME, Flack KD, et al. Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes. PLoS One. 2017;12(2):e0172610.
Davy, Brenda M., et al. “Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes.PLoS One, vol. 12, no. 2, 2017, p. e0172610. Pubmed, doi:10.1371/journal.pone.0172610.
Davy BM, Winett RA, Savla J, Marinik EL, Baugh ME, Flack KD, Halliday TM, Kelleher SA, Winett SG, Williams DM, Boshra S. Resist diabetes: A randomized clinical trial for resistance training maintenance in adults with prediabetes. PLoS One. 2017;12(2):e0172610.

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2017

Volume

12

Issue

2

Start / End Page

e0172610

Location

United States

Related Subject Headings

  • Sedentary Behavior
  • Resistance Training
  • Prediabetic State
  • Overweight
  • Muscle Strength
  • Middle Aged
  • Male
  • Humans
  • General Science & Technology
  • Female