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Gastrointestinal milk intolerance of infancy.

Publication ,  Journal Article
Berezin, S; Schwarz, SM; Glassman, M; Davidian, M; Newman, LJ
Published in: Am J Dis Child
March 1989

During a period of 30 months, cow's milk- or soy protein-induced colitis was diagnosed in 22 infants. All patients presented with hematochezia. Only three patients had substantial diarrhea. Colonoscopic evaluations demonstrated a characteristic mucosal appearance, manifested by aphthoid ulcerations with intervening, normal-appearing mucosa. Histologic findings included surface ulcerations and associated inflammation of the lamina propria and submucosa, marked by substantial eosinophilic infiltration. Both clinical symptoms and colonoscopic abnormalities rapidly resolved in all patients after the elimination of cow's milk and/or soy protein from the diet. These data indicate that hematochezia may be the predominant symptom of cow's milk protein and soy protein intolerance in many affected infants, and that colonoscopy is the most effective means of establishing a definitive diagnosis in this patient population.

Duke Scholars

Published In

Am J Dis Child

DOI

ISSN

0002-922X

Publication Date

March 1989

Volume

143

Issue

3

Start / End Page

361 / 362

Location

United States

Related Subject Headings

  • Soybean Proteins
  • Prospective Studies
  • Plant Proteins, Dietary
  • Milk Proteins
  • Intestinal Mucosa
  • Infant, Newborn
  • Infant
  • Humans
  • Glycine max
  • Gastrointestinal Hemorrhage
 

Citation

APA
Chicago
ICMJE
MLA
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Berezin, S., Schwarz, S. M., Glassman, M., Davidian, M., & Newman, L. J. (1989). Gastrointestinal milk intolerance of infancy. Am J Dis Child, 143(3), 361–362. https://doi.org/10.1001/archpedi.1989.02150150119029
Berezin, S., S. M. Schwarz, M. Glassman, M. Davidian, and L. J. Newman. “Gastrointestinal milk intolerance of infancy.Am J Dis Child 143, no. 3 (March 1989): 361–62. https://doi.org/10.1001/archpedi.1989.02150150119029.
Berezin S, Schwarz SM, Glassman M, Davidian M, Newman LJ. Gastrointestinal milk intolerance of infancy. Am J Dis Child. 1989 Mar;143(3):361–2.
Berezin, S., et al. “Gastrointestinal milk intolerance of infancy.Am J Dis Child, vol. 143, no. 3, Mar. 1989, pp. 361–62. Pubmed, doi:10.1001/archpedi.1989.02150150119029.
Berezin S, Schwarz SM, Glassman M, Davidian M, Newman LJ. Gastrointestinal milk intolerance of infancy. Am J Dis Child. 1989 Mar;143(3):361–362.

Published In

Am J Dis Child

DOI

ISSN

0002-922X

Publication Date

March 1989

Volume

143

Issue

3

Start / End Page

361 / 362

Location

United States

Related Subject Headings

  • Soybean Proteins
  • Prospective Studies
  • Plant Proteins, Dietary
  • Milk Proteins
  • Intestinal Mucosa
  • Infant, Newborn
  • Infant
  • Humans
  • Glycine max
  • Gastrointestinal Hemorrhage