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Biochemical and ultrastructural differences between muco-epidermoid and carcinoid tumors of the bronchus.

Publication ,  Journal Article
Feldman, JM; Benning, TL; Saltzman, H
Published in: J Surg Oncol
April 1988

Bronchial adenomas have been classified into three types: carcinoid tumors, cylindromas (adenoid cystic carcinomas), and mucoepidermoid tumors. Studies from our laboratory have demonstrated that the quantitative measurement of monoamine oxidase (MAO) in homogenates of carcinoid tumors of foregut origin is different than the activity enzymes in other tumors of neural crest origin. In this study we compared the biochemical composition of 12 bronchial carcinoid tumors with the biochemical composition of a rare mucoepidermoid adenoma of the bronchus. Electron microscopy revealed that some cells of the mucoepidermoid adenoma contained mucin and tonofilaments; none of the cells contained neurosecretory granules. The MAO activity of the bronchial carcinoid tumors was much higher than the MAO activity of the mucoepidermoid adenoma. Thus, there are distinctive ultrastructural and biochemical differences in these two types of bronchial adenomas.

Duke Scholars

Published In

J Surg Oncol

DOI

ISSN

0022-4790

Publication Date

April 1988

Volume

37

Issue

4

Start / End Page

227 / 231

Location

United States

Related Subject Headings

  • Serotonin
  • Oncology & Carcinogenesis
  • Monoamine Oxidase
  • Middle Aged
  • Male
  • Humans
  • Female
  • Carcinoma, Adenoid Cystic
  • Carcinoma
  • Carcinoid Tumor
 

Citation

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ICMJE
MLA
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Feldman, J. M., Benning, T. L., & Saltzman, H. (1988). Biochemical and ultrastructural differences between muco-epidermoid and carcinoid tumors of the bronchus. J Surg Oncol, 37(4), 227–231. https://doi.org/10.1002/jso.2930370403
Feldman, J. M., T. L. Benning, and H. Saltzman. “Biochemical and ultrastructural differences between muco-epidermoid and carcinoid tumors of the bronchus.J Surg Oncol 37, no. 4 (April 1988): 227–31. https://doi.org/10.1002/jso.2930370403.
Feldman JM, Benning TL, Saltzman H. Biochemical and ultrastructural differences between muco-epidermoid and carcinoid tumors of the bronchus. J Surg Oncol. 1988 Apr;37(4):227–31.
Feldman, J. M., et al. “Biochemical and ultrastructural differences between muco-epidermoid and carcinoid tumors of the bronchus.J Surg Oncol, vol. 37, no. 4, Apr. 1988, pp. 227–31. Pubmed, doi:10.1002/jso.2930370403.
Feldman JM, Benning TL, Saltzman H. Biochemical and ultrastructural differences between muco-epidermoid and carcinoid tumors of the bronchus. J Surg Oncol. 1988 Apr;37(4):227–231.
Journal cover image

Published In

J Surg Oncol

DOI

ISSN

0022-4790

Publication Date

April 1988

Volume

37

Issue

4

Start / End Page

227 / 231

Location

United States

Related Subject Headings

  • Serotonin
  • Oncology & Carcinogenesis
  • Monoamine Oxidase
  • Middle Aged
  • Male
  • Humans
  • Female
  • Carcinoma, Adenoid Cystic
  • Carcinoma
  • Carcinoid Tumor