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Coronary blood flow in chronic insulin-dependent diabetic dogs.

Publication ,  Journal Article
Small, KW; Stefansson, E; Hatchell, DL
Published in: Acta Diabetol Lat
1989

Diabetic patients appear to be at an increased risk for perioperative morbidity and mortality following coronary artery bypass grafting. Many have suggested that microangiopathy is a primary cause. Using radionuclide labelled microspheres, we measured the perfusion of the subendocardium, midmyocardium, subepicardium, and the subendocardium/subepicardium ratio in alloxan-induced diabetic and normal dogs. We found no statistical difference in the myocardial perfusion of dogs made diabetic for five months when compared to normal dogs. By using repeated measures two-factor analysis of variance-regression model, changing blood glucose levels had no effect on coronary blood flow in either the diabetic or normal dogs.

Duke Scholars

Published In

Acta Diabetol Lat

DOI

ISSN

0001-5563

Publication Date

1989

Volume

26

Issue

4

Start / End Page

275 / 282

Location

Italy

Related Subject Headings

  • Regression Analysis
  • Reference Values
  • Dogs
  • Diabetes Mellitus, Type 1
  • Diabetes Mellitus, Experimental
  • Coronary Circulation
  • Animals
  • Analysis of Variance
 

Citation

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Small, K. W., Stefansson, E., & Hatchell, D. L. (1989). Coronary blood flow in chronic insulin-dependent diabetic dogs. Acta Diabetol Lat, 26(4), 275–282. https://doi.org/10.1007/BF02624638
Small, K. W., E. Stefansson, and D. L. Hatchell. “Coronary blood flow in chronic insulin-dependent diabetic dogs.Acta Diabetol Lat 26, no. 4 (1989): 275–82. https://doi.org/10.1007/BF02624638.
Small KW, Stefansson E, Hatchell DL. Coronary blood flow in chronic insulin-dependent diabetic dogs. Acta Diabetol Lat. 1989;26(4):275–82.
Small, K. W., et al. “Coronary blood flow in chronic insulin-dependent diabetic dogs.Acta Diabetol Lat, vol. 26, no. 4, 1989, pp. 275–82. Pubmed, doi:10.1007/BF02624638.
Small KW, Stefansson E, Hatchell DL. Coronary blood flow in chronic insulin-dependent diabetic dogs. Acta Diabetol Lat. 1989;26(4):275–282.

Published In

Acta Diabetol Lat

DOI

ISSN

0001-5563

Publication Date

1989

Volume

26

Issue

4

Start / End Page

275 / 282

Location

Italy

Related Subject Headings

  • Regression Analysis
  • Reference Values
  • Dogs
  • Diabetes Mellitus, Type 1
  • Diabetes Mellitus, Experimental
  • Coronary Circulation
  • Animals
  • Analysis of Variance