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In the Wake of Systolic Blood Pressure Intervention Trial: New Targets for Improving Hypertension Management in Chronic Kidney Disease?

Publication ,  Journal Article
Tyson, CC; Coffman, TM
Published in: Nephron
2017

Systolic Blood Pressure Intervention Trial (SPRINT) was a multicenter randomized controlled trial showing the significant benefit of intensive reduction of blood pressure to a target of 120 mm Hg in individuals with hypertension and elevated cardiovascular risk. Because SPRINT includes the largest cohort of adults with chronic kidney disease (CKD) to be prospectively studied in a hypertension intervention trial, it has particular relevance to the field of nephrology. Here, we review the findings of SPRINT and assess their potential impact on guidelines for treatment of hypertension in patients with CKD. We believe that the data from SPRINT will support a recommendation for lowering blood pressure targets to 120 mm Hg in a substantial segment of adults with CKD.

Duke Scholars

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Published In

Nephron

DOI

EISSN

2235-3186

Publication Date

2017

Volume

135

Issue

4

Start / End Page

287 / 290

Location

Switzerland

Related Subject Headings

  • Urology & Nephrology
  • Risk Factors
  • Renal Insufficiency, Chronic
  • Practice Guidelines as Topic
  • Hypertension
  • Humans
  • Cardiovascular Diseases
  • Blood Pressure
  • Antihypertensive Agents
  • Adult
 

Citation

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Tyson, C. C., & Coffman, T. M. (2017). In the Wake of Systolic Blood Pressure Intervention Trial: New Targets for Improving Hypertension Management in Chronic Kidney Disease? Nephron, 135(4), 287–290. https://doi.org/10.1159/000455130
Tyson, Crystal C., and Thomas M. Coffman. “In the Wake of Systolic Blood Pressure Intervention Trial: New Targets for Improving Hypertension Management in Chronic Kidney Disease?Nephron 135, no. 4 (2017): 287–90. https://doi.org/10.1159/000455130.
Tyson, Crystal C., and Thomas M. Coffman. “In the Wake of Systolic Blood Pressure Intervention Trial: New Targets for Improving Hypertension Management in Chronic Kidney Disease?Nephron, vol. 135, no. 4, 2017, pp. 287–90. Pubmed, doi:10.1159/000455130.
Journal cover image

Published In

Nephron

DOI

EISSN

2235-3186

Publication Date

2017

Volume

135

Issue

4

Start / End Page

287 / 290

Location

Switzerland

Related Subject Headings

  • Urology & Nephrology
  • Risk Factors
  • Renal Insufficiency, Chronic
  • Practice Guidelines as Topic
  • Hypertension
  • Humans
  • Cardiovascular Diseases
  • Blood Pressure
  • Antihypertensive Agents
  • Adult