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Bone contusion progression from traumatic knee injury: association of rate of contusion resolution with injury severity.

Publication ,  Journal Article
Pedersen, DR; El-Khoury, GY; Thedens, DR; Saad-Eldine, M; Phisitkul, P; Amendola, A
Published in: Open Access J Sports Med
2017

BACKGROUND: Bone contusions are frequently encountered in magnetic resonance imaging (MRI) evaluation of knee anterior cruciate ligament (ACL) injuries. Their role as indicators of injury severity remains unclear, primarily due to indeterminate levels of joint injury forces and to a lack of preinjury imaging. PURPOSE: The purpose of this study was to 1) quantify bone contusion pathogenesis following traumatic joint injuries using fixed imaging follow-ups, and 2) assess the feasibility of using longitudinal bone contusion volumes as an indicator of knee injury severity. STUDY DESIGN: Prospective sequential MRI follow-ups of a goat cohort exposed to controlled stifle trauma in vivo were compared to parallel clinical MRI follow-ups of a human ACL tear patient series. METHODS: Reproducible cartilage impact damage of various energy magnitudes was applied in a survival goat model, coupled with partial resection of anterior portions of medial menisci. Both emulate injury patterns to the knee osteochondral structures commonly encountered in human ACL injury imaging as well as instability from resultant ligament laxity. Longitudinal clinical MRI sequences portrayed stifle bone contusion evolution through 6 months after the inciting event. RESULTS: In the first 2 weeks, biological response variability dominated the whole-joint response with no apparent correlation to trauma severity. Control goats subjected to partial meniscectomy alone exhibited minimal bone response. Thereafter, 0.6 J impact bone contusions portrayed a faster rate of resolution than those induced by 1.2 J cartilage impacts. CONCLUSION: Bone contusion sizes combined with time of persistence are likely better measures of joint injury severity than isolated bone contusion volume.

Duke Scholars

Published In

Open Access J Sports Med

DOI

ISSN

1179-1543

Publication Date

2017

Volume

8

Start / End Page

9 / 15

Location

New Zealand

Related Subject Headings

  • 4207 Sports science and exercise
  • 3202 Clinical sciences
  • 1106 Human Movement and Sports Sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Pedersen, D. R., El-Khoury, G. Y., Thedens, D. R., Saad-Eldine, M., Phisitkul, P., & Amendola, A. (2017). Bone contusion progression from traumatic knee injury: association of rate of contusion resolution with injury severity. Open Access J Sports Med, 8, 9–15. https://doi.org/10.2147/OAJSM.S118811
Pedersen, Douglas R., Georges Y. El-Khoury, Dan R. Thedens, Mothana Saad-Eldine, Phinit Phisitkul, and Annunziato Amendola. “Bone contusion progression from traumatic knee injury: association of rate of contusion resolution with injury severity.Open Access J Sports Med 8 (2017): 9–15. https://doi.org/10.2147/OAJSM.S118811.
Pedersen DR, El-Khoury GY, Thedens DR, Saad-Eldine M, Phisitkul P, Amendola A. Bone contusion progression from traumatic knee injury: association of rate of contusion resolution with injury severity. Open Access J Sports Med. 2017;8:9–15.
Pedersen, Douglas R., et al. “Bone contusion progression from traumatic knee injury: association of rate of contusion resolution with injury severity.Open Access J Sports Med, vol. 8, 2017, pp. 9–15. Pubmed, doi:10.2147/OAJSM.S118811.
Pedersen DR, El-Khoury GY, Thedens DR, Saad-Eldine M, Phisitkul P, Amendola A. Bone contusion progression from traumatic knee injury: association of rate of contusion resolution with injury severity. Open Access J Sports Med. 2017;8:9–15.

Published In

Open Access J Sports Med

DOI

ISSN

1179-1543

Publication Date

2017

Volume

8

Start / End Page

9 / 15

Location

New Zealand

Related Subject Headings

  • 4207 Sports science and exercise
  • 3202 Clinical sciences
  • 1106 Human Movement and Sports Sciences
  • 1103 Clinical Sciences