CT attenuation of unilocular pancreatic cystic lesions to differentiate pseudocysts from mucin-containing cysts.
There is extensive overlap among the imaging characteristics of pseudocyst, mucinous cystic neoplasm (MCN) and side branch intraductal papillary mucinous neoplasm (IPMN) on CT images.The purpose of this study was to evaluate the usefulness of attenuation measurement in differentiating pseudocysts from MCN and IPMN of pancreas on CT images.Seventy-five pathologically proven unilocular pancreatic cysts including 31 pseudocysts, 29 MCN and 15 IPMN imaged with multidetector computed tomography (MDCT) before resection were evaluated.Attenuation values were measured by conventional region of interest (ROI) method.Attenuation values (in Hounsfield unit, HU) were compared between the cyst pathologies. Receiver operating characteristic (ROC) curve analysis was performed to obtain the best attenuation threshold between mucin-containing cysts and pseudocysts. Correlation between attenuation values and cyst size was assessed.Maximum transaxial diameters of pseudocysts (4.5 cm), MCNs (3.7 cm) and IPMNs (4.0 cm) were comparable (P=0.919). Mean attenuation was 18.9 HU, 13.0 HU and 11.4 HU for pseudocyst, MCNs and IPMNs, respectively. Attenuations were significantly higher in pseudocysts versus mucin-containing (MCN+IPMN) cysts (P=0.001) and comparable between MCNs and IPMNs (P=0.390). ROC curve showed 14.5 HU the best cut-off (accuracy: 73.5%) for differentiating pseudocysts from mucin-containing cysts (P<0.001). Pancreatic cyst attenuation measurement did not significantly correlate with cyst size (r=-0.03, P=0.772).Attenuation measurement may help in differentiating pseudocysts from unilocular mucin-containing simple cysts of the pancreas on CT images.
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Related Subject Headings
- Young Adult
- Retrospective Studies
- Pancreatic Pseudocyst
- Pancreatic Neoplasms
- Pancreatic Cyst
- Multidetector Computed Tomography
- Mucins
- Middle Aged
- Male
- Humans
Citation
Published In
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Young Adult
- Retrospective Studies
- Pancreatic Pseudocyst
- Pancreatic Neoplasms
- Pancreatic Cyst
- Multidetector Computed Tomography
- Mucins
- Middle Aged
- Male
- Humans