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Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis.

Publication ,  Journal Article
Lazarus, GS; Yost, FJ; Thomas, CA
Published in: Science
December 16, 1977

Extracts of involved and uninvolved skin from nine patients with untreated psoriasis were studied for chemotactic activity. Psoriatic plaque contains increased amounts of a complement-dependent chemotactic factor that is inhibited by diisopropyl fluorophosphate. This factor may be human skin serine proteinase.

Duke Scholars

Published In

Science

DOI

ISSN

0036-8075

Publication Date

December 16, 1977

Volume

198

Issue

4322

Start / End Page

1162 / 1163

Location

United States

Related Subject Headings

  • Psoriasis
  • Protease Inhibitors
  • Peptide Hydrolases
  • Neutrophils
  • Mice
  • Isoflurophate
  • Humans
  • General Science & Technology
  • Complement System Proteins
  • Chemotaxis, Leukocyte
 

Citation

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ICMJE
MLA
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Lazarus, G. S., Yost, F. J., & Thomas, C. A. (1977). Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis. Science, 198(4322), 1162–1163. https://doi.org/10.1126/science.929193
Lazarus, G. S., F. J. Yost, and C. A. Thomas. “Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis.Science 198, no. 4322 (December 16, 1977): 1162–63. https://doi.org/10.1126/science.929193.
Lazarus GS, Yost FJ, Thomas CA. Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis. Science. 1977 Dec 16;198(4322):1162–3.
Lazarus, G. S., et al. “Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis.Science, vol. 198, no. 4322, Dec. 1977, pp. 1162–63. Pubmed, doi:10.1126/science.929193.
Lazarus GS, Yost FJ, Thomas CA. Polymorphonuclear leukocytes: possible mechanism of accumulation in psoriasis. Science. 1977 Dec 16;198(4322):1162–1163.
Journal cover image

Published In

Science

DOI

ISSN

0036-8075

Publication Date

December 16, 1977

Volume

198

Issue

4322

Start / End Page

1162 / 1163

Location

United States

Related Subject Headings

  • Psoriasis
  • Protease Inhibitors
  • Peptide Hydrolases
  • Neutrophils
  • Mice
  • Isoflurophate
  • Humans
  • General Science & Technology
  • Complement System Proteins
  • Chemotaxis, Leukocyte