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Young inversion with multiple linked QTLs under selection in a hybrid zone.

Publication ,  Journal Article
Lee, C-R; Wang, B; Mojica, JP; Mandáková, T; Prasad, KVSK; Goicoechea, JL; Perera, N; Hellsten, U; Hundley, HN; Johnson, J; Grimwood, J; Yu, Y ...
Published in: Nature ecology & evolution
April 2017

Fixed chromosomal inversions can reduce gene flow and promote speciation in two ways: by suppressing recombination and by carrying locally favoured alleles at multiple loci. However, it is unknown whether favoured mutations slowly accumulate on older inversions or if young inversions spread because they capture pre-existing adaptive quantitative trait loci (QTLs). By genetic mapping, chromosome painting and genome sequencing, we have identified a major inversion controlling ecologically important traits in Boechera stricta. The inversion arose since the last glaciation and subsequently reached local high frequency in a hybrid speciation zone. Furthermore, the inversion shows signs of positive directional selection. To test whether the inversion could have captured existing, linked QTLs, we crossed standard, collinear haplotypes from the hybrid zone and found multiple linked phenology QTLs within the inversion region. These findings provide the first direct evidence that linked, locally adapted QTLs may be captured by young inversions during incipient speciation.

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Published In

Nature ecology & evolution

DOI

EISSN

2397-334X

ISSN

2397-334X

Publication Date

April 2017

Volume

1

Issue

5

Start / End Page

119

Related Subject Headings

  • 4104 Environmental management
  • 3104 Evolutionary biology
  • 3103 Ecology
 

Citation

APA
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MLA
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Lee, C.-R., Wang, B., Mojica, J. P., Mandáková, T., Prasad, K. V. S. K., Goicoechea, J. L., … Mitchell-Olds, T. (2017). Young inversion with multiple linked QTLs under selection in a hybrid zone. Nature Ecology & Evolution, 1(5), 119. https://doi.org/10.1038/s41559-017-0119
Lee, Cheng-Ruei, Baosheng Wang, Julius P. Mojica, Terezie Mandáková, Kasavajhala V. S. K. Prasad, Jose Luis Goicoechea, Nadeesha Perera, et al. “Young inversion with multiple linked QTLs under selection in a hybrid zone.Nature Ecology & Evolution 1, no. 5 (April 2017): 119. https://doi.org/10.1038/s41559-017-0119.
Lee C-R, Wang B, Mojica JP, Mandáková T, Prasad KVSK, Goicoechea JL, et al. Young inversion with multiple linked QTLs under selection in a hybrid zone. Nature ecology & evolution. 2017 Apr;1(5):119.
Lee, Cheng-Ruei, et al. “Young inversion with multiple linked QTLs under selection in a hybrid zone.Nature Ecology & Evolution, vol. 1, no. 5, Apr. 2017, p. 119. Epmc, doi:10.1038/s41559-017-0119.
Lee C-R, Wang B, Mojica JP, Mandáková T, Prasad KVSK, Goicoechea JL, Perera N, Hellsten U, Hundley HN, Johnson J, Grimwood J, Barry K, Fairclough S, Jenkins JW, Yu Y, Kudrna D, Zhang J, Talag J, Golser W, Ghattas K, Schranz ME, Wing R, Lysak MA, Schmutz J, Rokhsar DS, Mitchell-Olds T. Young inversion with multiple linked QTLs under selection in a hybrid zone. Nature ecology & evolution. 2017 Apr;1(5):119.

Published In

Nature ecology & evolution

DOI

EISSN

2397-334X

ISSN

2397-334X

Publication Date

April 2017

Volume

1

Issue

5

Start / End Page

119

Related Subject Headings

  • 4104 Environmental management
  • 3104 Evolutionary biology
  • 3103 Ecology