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Resistance to narrowband ultraviolet B therapy over varicose veins in two cases of generalized vitiligo

Publication ,  Journal Article
Roth, GM; Holcomb, ZE; Brown, B; Fine, JD; Powers, JG
Published in: Journal of the Dermatology Nurses' Association
June 1, 2017

Vitiligo is a difficult-to-control disease with a devastating impact in the lives of many patients. An association has been shown between the Koebner phenomenon and the occurrence of skin depigmentation in vitiligo. However, the medical literature contains very little information regarding the relationship between varicose veins, a common comorbidity formany patients, and vitiligo skin lesions. We present two cases of generalized vitiligo in which patients experienced delayed or absent repigmentation exclusively over varicose veins after narrowband ultraviolet B therapy, despite repigmentation over the rest of the body. In one case, repigmentation occurred after varicose vein treatment. These patients highlight potential and previously unexplored interactions between varicose veins and response to vitiligo phototherapy. The impact of varicose veins on vitiligo treatment may inform future research ideas into the pathogenesis of this skin disease. Furthermore, these cases suggest a possible mechanism of improving local treatment response in vitiligo by addressing underlying varicose veins

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Published In

Journal of the Dermatology Nurses' Association

DOI

ISSN

1945-760X

Publication Date

June 1, 2017

Volume

9

Issue

3

Start / End Page

139 / 140
 

Citation

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Roth, G. M., Holcomb, Z. E., Brown, B., Fine, J. D., & Powers, J. G. (2017). Resistance to narrowband ultraviolet B therapy over varicose veins in two cases of generalized vitiligo. Journal of the Dermatology Nurses’ Association, 9(3), 139–140. https://doi.org/10.1097/JDN.0000000000000300
Roth, G. M., Z. E. Holcomb, B. Brown, J. D. Fine, and J. G. Powers. “Resistance to narrowband ultraviolet B therapy over varicose veins in two cases of generalized vitiligo.” Journal of the Dermatology Nurses’ Association 9, no. 3 (June 1, 2017): 139–40. https://doi.org/10.1097/JDN.0000000000000300.
Roth GM, Holcomb ZE, Brown B, Fine JD, Powers JG. Resistance to narrowband ultraviolet B therapy over varicose veins in two cases of generalized vitiligo. Journal of the Dermatology Nurses’ Association. 2017 Jun 1;9(3):139–40.
Roth, G. M., et al. “Resistance to narrowband ultraviolet B therapy over varicose veins in two cases of generalized vitiligo.” Journal of the Dermatology Nurses’ Association, vol. 9, no. 3, June 2017, pp. 139–40. Scopus, doi:10.1097/JDN.0000000000000300.
Roth GM, Holcomb ZE, Brown B, Fine JD, Powers JG. Resistance to narrowband ultraviolet B therapy over varicose veins in two cases of generalized vitiligo. Journal of the Dermatology Nurses’ Association. 2017 Jun 1;9(3):139–140.

Published In

Journal of the Dermatology Nurses' Association

DOI

ISSN

1945-760X

Publication Date

June 1, 2017

Volume

9

Issue

3

Start / End Page

139 / 140