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TH‐D‐351‐02: A Novel Digital Tomosynthesis (DTS) Reconstruction Method Using Prior Information and a Deformation Model

Publication ,  Conference
Ren, L; Zhang, J; Thongphiew, D; Godfrey, D; Zhou, S; Yin, F
Published in: Medical Physics
January 1, 2008

Purpose: Digital Tomosynthesis (DTS) is a quasi‐3D imaging technique which reconstructs images from a limited angle of on‐board projections with significantly lower dose and shorter acquisition time than full cone‐beam CT (CBCT). However, DTS images reconstructed by the conventional filtered back projection method have low plane‐to‐plane resolution and can't provide full volumetric information for target localization. In this study, we developed a novel DTS reconstruction method using prior information and a deformation model to recover volumetric information. Method and Materials: A patient's previous CBCT or CT data were used as the prior information, and the new patient volume was considered as a deformation of the prior volume. The deformation fields were solved by minimizing bending energy and maintaining data fidelity. A nonlinear conjugate gradient method was used as the optimizer. The algorithm was tested using simulated projections of a Shepp‐Logan phantom, liver and head‐and‐neck patient data. The accuracy of the reconstruction was evaluated by comparing both pixel value and contour differences between DTS and CBCT images. Results: In the liver patient study, the systematic and random errors for the live contour reconstructed using a 60‐degree scan angle were 0.5 and 1.6mm, respectively, showing the new organ volume was accurately reconstructed. The pixel signal‐to‐noise ratio (PSNR) for 60‐degree DTS reaches 23.5dB. In the head‐and‐neck patient study, the method using 60‐degree scan was able to reconstruct the 8.1 degree rotation of the bony structure with 0.0 degree error. The PSNR for 60‐degree DTS reaches 24.2dB. Conclusion: A novel reconstruction method was developed to reconstruct DTS images using prior information and a deformation model. Volumetric information was accurately obtained using a 60‐degree scan angle. Preliminary validation of the algorithm showed that it is both technically and clinically feasible for image‐guidance in radiation therapy. Partially supported by Grants from NIH and Varian Medical Systems. © 2008, American Association of Physicists in Medicine. All rights reserved.

Duke Scholars

Published In

Medical Physics

DOI

ISSN

0094-2405

Publication Date

January 1, 2008

Volume

35

Issue

6

Start / End Page

2989

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Ren, L., Zhang, J., Thongphiew, D., Godfrey, D., Zhou, S., & Yin, F. (2008). TH‐D‐351‐02: A Novel Digital Tomosynthesis (DTS) Reconstruction Method Using Prior Information and a Deformation Model. In Medical Physics (Vol. 35, p. 2989). https://doi.org/10.1118/1.2962923
Ren, L., J. Zhang, D. Thongphiew, D. Godfrey, S. Zhou, and F. Yin. “TH‐D‐351‐02: A Novel Digital Tomosynthesis (DTS) Reconstruction Method Using Prior Information and a Deformation Model.” In Medical Physics, 35:2989, 2008. https://doi.org/10.1118/1.2962923.
Ren L, Zhang J, Thongphiew D, Godfrey D, Zhou S, Yin F. TH‐D‐351‐02: A Novel Digital Tomosynthesis (DTS) Reconstruction Method Using Prior Information and a Deformation Model. In: Medical Physics. 2008. p. 2989.
Ren, L., et al. “TH‐D‐351‐02: A Novel Digital Tomosynthesis (DTS) Reconstruction Method Using Prior Information and a Deformation Model.” Medical Physics, vol. 35, no. 6, 2008, p. 2989. Scopus, doi:10.1118/1.2962923.
Ren L, Zhang J, Thongphiew D, Godfrey D, Zhou S, Yin F. TH‐D‐351‐02: A Novel Digital Tomosynthesis (DTS) Reconstruction Method Using Prior Information and a Deformation Model. Medical Physics. 2008. p. 2989.

Published In

Medical Physics

DOI

ISSN

0094-2405

Publication Date

January 1, 2008

Volume

35

Issue

6

Start / End Page

2989

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences