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SU‐FF‐T‐567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment

Publication ,  Conference
Wu, Q; Yoo, S; Kirkpatrick, J; Mcmahon, R; Thongphiew, D; Yin, F
Published in: Medical Physics
January 1, 2009

Purpose: Volumetric modulated arc treatment (VMAT) reduces treatment time over static beam intensity modulated treatment (IMRT) by delivering IMRT using arcs. This clinical study evaluates the feasibility of using VMAT for spine stereotactic body radiotherapy (SBRT) to achieve highly conformal dose distributions that spare adjacent OARs with reduced treatment time. Methods and Materials: Ten spine SBRT patients were studied retrospectively. IMRT and VMAT plans (one and two arc plans) were generated for each patient. PTV dose coverage, OAR dose sparing, and normal tissue integral dose were measured and compared. Differences in treatment delivery were also analyzed by comparing MLC segments, total MUs, and total treatment time. Results: The PTV DVHs were comparable between the VMAT and the IMRT plans in the shoulder (D99%‐D90%), slope (D90%‐D10%), and tail (D10%‐D1%) regions. When averaged over all patients, only VMAT2arc had a better conformity index than IMRT (1.09 vs.1.15, p=0.007). In terms of cord sparing, IMRT was the best and VMAT1arc was the worst. IMRT achieved >10% more D1% cord sparing for 6 out of 10 cases and 7–15% more D10% sparing over the VMAT1arc. For cord sparing, the difference between IMRT and VMAT2arc were smaller and statistically insignificant at all dose levels. Differences for other OARs were small and statistically insignificant. The mean MUs and treatment times were (8711MU, 15.86min), (7730MU, 8.56min) and (6317MU, 7.88min) for IMRT, VMAT1arc and VMAT2arc plans, respectively. The average integral dose was the lowest for IMRT and the highest for VMAT1arc. However, the difference was statistically insignificant. Conclusions: Although VMAT provided comparable PTV coverage and esophagus sparing for spine SBRT, VMAT1arc showed significantly worse cord sparing than IMRT, while VMAT2arc was comparable to IMRT. Treatment efficiency is substantially improved with the VMAT technique. © 2009, American Association of Physicists in Medicine. All rights reserved.

Duke Scholars

Published In

Medical Physics

DOI

ISSN

0094-2405

Publication Date

January 1, 2009

Volume

36

Issue

6

Start / End Page

2655

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Wu, Q., Yoo, S., Kirkpatrick, J., Mcmahon, R., Thongphiew, D., & Yin, F. (2009). SU‐FF‐T‐567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment. In Medical Physics (Vol. 36, p. 2655). https://doi.org/10.1118/1.3182065
Wu, Q., S. Yoo, J. Kirkpatrick, R. Mcmahon, D. Thongphiew, and F. Yin. “SU‐FF‐T‐567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment.” In Medical Physics, 36:2655, 2009. https://doi.org/10.1118/1.3182065.
Wu Q, Yoo S, Kirkpatrick J, Mcmahon R, Thongphiew D, Yin F. SU‐FF‐T‐567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment. In: Medical Physics. 2009. p. 2655.
Wu, Q., et al. “SU‐FF‐T‐567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment.” Medical Physics, vol. 36, no. 6, 2009, p. 2655. Scopus, doi:10.1118/1.3182065.
Wu Q, Yoo S, Kirkpatrick J, Mcmahon R, Thongphiew D, Yin F. SU‐FF‐T‐567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment. Medical Physics. 2009. p. 2655.

Published In

Medical Physics

DOI

ISSN

0094-2405

Publication Date

January 1, 2009

Volume

36

Issue

6

Start / End Page

2655

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • 5105 Medical and biological physics
  • 4003 Biomedical engineering
  • 1112 Oncology and Carcinogenesis
  • 0903 Biomedical Engineering
  • 0299 Other Physical Sciences