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How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)?

Publication ,  Conference
Mein, S; Rankine, L; Miles, D; Juang, T; Cai, B; Curcuru, A; Mutic, S; Fenoli, J; Adamovics, J; Li, H; Oldham, M
Published in: Journal of Physics: Conference Series
June 5, 2017

To develop and apply a remote dosimetry protocol with PRESAGE® radiochromic plastic and optical-CT readout in the validation of MRI guided radiation therapy (MRgRT) treatments (MRIdian® by ViewRay®). Through multi-institutional collaboration we performed PRESAGE® dosimetry studies in 4ml cuvettes to investigate dose-response linearity, MR-compatibility, and energy-independence. An open calibration field and symmetrical 3-field plans were delivered to 10cm diameter PRESAGE® to examine percent depth dose and response uniformity under a magnetic field. Evidence of non-linear dose response led to a large volume PRESAGE® study where small corrections were developed for temporally- and spatially-dependent behaviors observed between irradiation and delayed readout. TG-119 plans were created in the MRIdian® TPS and then delivered to 14.5cm 2kg PRESAGE® dosimeters. Through the domestic investigation of an off-site MRgRT system, a refined 3D remote dosimetry protocol is presented capable of validation of advanced MRgRT radiation treatments.

Duke Scholars

Published In

Journal of Physics: Conference Series

DOI

EISSN

1742-6596

ISSN

1742-6588

Publication Date

June 5, 2017

Volume

847

Issue

1

Related Subject Headings

  • 51 Physical sciences
  • 0299 Other Physical Sciences
  • 0204 Condensed Matter Physics
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
 

Citation

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Mein, S., Rankine, L., Miles, D., Juang, T., Cai, B., Curcuru, A., … Oldham, M. (2017). How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)? In Journal of Physics: Conference Series (Vol. 847). https://doi.org/10.1088/1742-6596/847/1/012056
Mein, S., L. Rankine, D. Miles, T. Juang, B. Cai, A. Curcuru, S. Mutic, et al. “How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)?” In Journal of Physics: Conference Series, Vol. 847, 2017. https://doi.org/10.1088/1742-6596/847/1/012056.
Mein S, Rankine L, Miles D, Juang T, Cai B, Curcuru A, et al. How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)? In: Journal of Physics: Conference Series. 2017.
Mein, S., et al. “How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)?Journal of Physics: Conference Series, vol. 847, no. 1, 2017. Scopus, doi:10.1088/1742-6596/847/1/012056.
Mein S, Rankine L, Miles D, Juang T, Cai B, Curcuru A, Mutic S, Fenoli J, Adamovics J, Li H, Oldham M. How feasible is remote 3D dosimetry for MR guided Radiation Therapy (MRgRT)? Journal of Physics: Conference Series. 2017.
Journal cover image

Published In

Journal of Physics: Conference Series

DOI

EISSN

1742-6596

ISSN

1742-6588

Publication Date

June 5, 2017

Volume

847

Issue

1

Related Subject Headings

  • 51 Physical sciences
  • 0299 Other Physical Sciences
  • 0204 Condensed Matter Physics
  • 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics