Skip to main content
Journal cover image

Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group.

Publication ,  Journal Article
Palmer, EA; Flynn, JT; Hardy, RJ; Phelps, DL; Phillips, CL; Schaffer, DB; Tung, B
Published in: Ophthalmology
November 1991

In the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity (ROP), 4099 infants weighing less than 1251 g at birth underwent sequential ophthalmic examinations, beginning at age 4 to 6 weeks, to monitor the incidence and course of ROP. Overall, 65.8% of the infants developed ROP to some degree; 81.6% for infants of less than 1000 g birth weight. As expected, ROP incidence and severity were higher in lower birth weight and gestational age categories. Black infants appeared less susceptible to ROP, of all severity categories, than nonblack infants. The timing of retinal vascular events correlated more closely with postconceptional age than with postnatal age, implicating the level of maturity more than postnatal environmental influences in governing the timing of these vascular events. These results include the current incidence of various severity stages of ROP found in the United States and provide new insight into the development of ROP.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Ophthalmology

DOI

ISSN

0161-6420

Publication Date

November 1991

Volume

98

Issue

11

Start / End Page

1628 / 1640

Location

United States

Related Subject Headings

  • United States
  • Retinopathy of Prematurity
  • Retinal Vessels
  • Ophthalmology & Optometry
  • Male
  • Infant, Newborn
  • Infant, Low Birth Weight
  • Infant
  • Incidence
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Palmer, E. A., Flynn, J. T., Hardy, R. J., Phelps, D. L., Phillips, C. L., Schaffer, D. B., & Tung, B. (1991). Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology, 98(11), 1628–1640. https://doi.org/10.1016/s0161-6420(91)32074-8
Palmer, E. A., J. T. Flynn, R. J. Hardy, D. L. Phelps, C. L. Phillips, D. B. Schaffer, and B. Tung. “Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group.Ophthalmology 98, no. 11 (November 1991): 1628–40. https://doi.org/10.1016/s0161-6420(91)32074-8.
Palmer EA, Flynn JT, Hardy RJ, Phelps DL, Phillips CL, Schaffer DB, et al. Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology. 1991 Nov;98(11):1628–40.
Palmer, E. A., et al. “Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group.Ophthalmology, vol. 98, no. 11, Nov. 1991, pp. 1628–40. Pubmed, doi:10.1016/s0161-6420(91)32074-8.
Palmer EA, Flynn JT, Hardy RJ, Phelps DL, Phillips CL, Schaffer DB, Tung B. Incidence and early course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Ophthalmology. 1991 Nov;98(11):1628–1640.
Journal cover image

Published In

Ophthalmology

DOI

ISSN

0161-6420

Publication Date

November 1991

Volume

98

Issue

11

Start / End Page

1628 / 1640

Location

United States

Related Subject Headings

  • United States
  • Retinopathy of Prematurity
  • Retinal Vessels
  • Ophthalmology & Optometry
  • Male
  • Infant, Newborn
  • Infant, Low Birth Weight
  • Infant
  • Incidence
  • Humans