Management of glioblastoma in elderly patients.
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults over 55years of age. The median age of diagnosis for patients with GBM is 64years old, with the incidence of patients between 75 and 85 increasing. The optimal treatment paradigm for elderly GBM patients continues to evolve due to the higher frequency of age-related and/or medical co-morbidities. Geriatric GBM patients have historically been excluded from larger, controlled clinical trials due to their presumed decreased likelihood of a sustained treatment response and/or a prolonged good outcome. Here, we highlight current treatment considerations of elderly GBM patients with respect to surgical, radiotherapeutic and systemic modalities, with considerations for improving future clinical outcomes for this patient population.
Duke Scholars
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- Humans
- Glioblastoma
- Disease Management
- Brain Neoplasms
- Aged, 80 and over
- Aged
- 5202 Biological psychology
- 3209 Neurosciences
- 3202 Clinical sciences
- 1701 Psychology
Citation
Published In
DOI
EISSN
Publication Date
Volume
Start / End Page
Location
Related Subject Headings
- Humans
- Glioblastoma
- Disease Management
- Brain Neoplasms
- Aged, 80 and over
- Aged
- 5202 Biological psychology
- 3209 Neurosciences
- 3202 Clinical sciences
- 1701 Psychology