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Handbook of Natural Computing

Engineering natural computation by autonomous DNA-based biomolecular devices

Publication ,  Chapter
Reif, JH; LaBean, TH
January 1, 2012

This chapter overviews the past and current state of a selected part of the emerging research area of DNA-based biomolecular devices. We particularly emphasize molecular devices that are: autonomous, executing steps with no exterior mediation after starting; and programmable, the tasks executed can be modified without entirely redesigning the nanostructure. We discuss work in this area that makes use of synthetic DNA to self-assemble into DNA nanostructure devices. Recently, there has been a series of impressive experimental results that have taken the technology from a state of intriguing possibilities into demonstrated capabilities of quickly increasing scale. We discuss various such programmable molecular-scale devices that achieve: computation, 2D patterning, amplified sensing, and molecular or nanoscale transport. This article is written for a general audience, and particularly emphasizes the interdisciplinary aspects of this quickly evolving and exciting field.

Duke Scholars

DOI

ISBN

9783540929093

Publication Date

January 1, 2012

Volume

3-4

Start / End Page

1320 / 1353
 

Citation

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Reif, J. H., & LaBean, T. H. (2012). Engineering natural computation by autonomous DNA-based biomolecular devices. In Handbook of Natural Computing (Vol. 3–4, pp. 1320–1353). https://doi.org/10.1007/978-3-540-92910-9_39
Reif, J. H., and T. H. LaBean. “Engineering natural computation by autonomous DNA-based biomolecular devices.” In Handbook of Natural Computing, 3–4:1320–53, 2012. https://doi.org/10.1007/978-3-540-92910-9_39.
Reif JH, LaBean TH. Engineering natural computation by autonomous DNA-based biomolecular devices. In: Handbook of Natural Computing. 2012. p. 1320–53.
Reif, J. H., and T. H. LaBean. “Engineering natural computation by autonomous DNA-based biomolecular devices.” Handbook of Natural Computing, vol. 3–4, 2012, pp. 1320–53. Scopus, doi:10.1007/978-3-540-92910-9_39.
Reif JH, LaBean TH. Engineering natural computation by autonomous DNA-based biomolecular devices. Handbook of Natural Computing. 2012. p. 1320–1353.
Journal cover image

DOI

ISBN

9783540929093

Publication Date

January 1, 2012

Volume

3-4

Start / End Page

1320 / 1353