Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi.
Publication
, Journal Article
McCarthy, MW; Kontoyiannis, DP; Cornely, OA; Perfect, JR; Walsh, TJ
Published in: J Infect Dis
August 15, 2017
The emergence of drug-resistant fungi poses a major threat to human health. Despite advances in preventive, diagnostic, and therapeutic interventions, resistant fungal infections continue to cause significant morbidity and mortality in patients with compromised immunity, underscoring the urgent need for new antifungal agents. In this article, we review the challenges associated with identifying broad-spectrum antifungal drugs and highlight novel targets that could enhance the armamentarium of agents available to treat drug-resistant invasive fungal infections.
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Published In
J Infect Dis
DOI
EISSN
1537-6613
Publication Date
August 15, 2017
Volume
216
Issue
suppl_3
Start / End Page
S474 / S483
Location
United States
Related Subject Headings
- Signal Transduction
- Microbiology
- Invasive Fungal Infections
- Humans
- Fungi
- Drug Resistance, Multiple, Fungal
- Disease Models, Animal
- Antifungal Agents
- Animals
- 42 Health sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
McCarthy, M. W., Kontoyiannis, D. P., Cornely, O. A., Perfect, J. R., & Walsh, T. J. (2017). Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi. J Infect Dis, 216(suppl_3), S474–S483. https://doi.org/10.1093/infdis/jix130
McCarthy, Matthew W., Dimitrios P. Kontoyiannis, Oliver A. Cornely, John R. Perfect, and Thomas J. Walsh. “Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi.” J Infect Dis 216, no. suppl_3 (August 15, 2017): S474–83. https://doi.org/10.1093/infdis/jix130.
McCarthy MW, Kontoyiannis DP, Cornely OA, Perfect JR, Walsh TJ. Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi. J Infect Dis. 2017 Aug 15;216(suppl_3):S474–83.
McCarthy, Matthew W., et al. “Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi.” J Infect Dis, vol. 216, no. suppl_3, Aug. 2017, pp. S474–83. Pubmed, doi:10.1093/infdis/jix130.
McCarthy MW, Kontoyiannis DP, Cornely OA, Perfect JR, Walsh TJ. Novel Agents and Drug Targets to Meet the Challenges of Resistant Fungi. J Infect Dis. 2017 Aug 15;216(suppl_3):S474–S483.
Published In
J Infect Dis
DOI
EISSN
1537-6613
Publication Date
August 15, 2017
Volume
216
Issue
suppl_3
Start / End Page
S474 / S483
Location
United States
Related Subject Headings
- Signal Transduction
- Microbiology
- Invasive Fungal Infections
- Humans
- Fungi
- Drug Resistance, Multiple, Fungal
- Disease Models, Animal
- Antifungal Agents
- Animals
- 42 Health sciences