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Pentacam tomograms: a novel method for quantification of posterior capsule opacification.

Publication ,  Journal Article
Grewal, D; Jain, R; Brar, GS; Grewal, SPS
Published in: Invest Ophthalmol Vis Sci
May 2008

PURPOSE: To develop and validate a method to quantify posterior capsule opacification (PCO) in eyes after cataract surgery and intraocular lens implantation using Scheimpflug Pentacam tomograms and compare its validity with slit lamp retroillumination image analysis. METHODS: One hundred twenty-four pseudophakic eyes of 124 patients were divided into two groups. Group 1 consisted of 40 eyes with visually significant PCO, and group 2 consisted of 84 eyes without visually significant PCO. Pentacam Imaging was performed after full mydriasis using the 50-scan acquisition protocol, and high-resolution tomograms were reconstructed and analyzed using ImageJ freeware. Retroillumination photographs were captured for group 1 eyes using the Topcon digital slit lamp, and these were analyzed using POCOman software to calculate an aggregate severity grade and percentage PCO value. Correlation coefficients were calculated for PCO values obtained using POCOman and ImageJ. RESULTS: Mean PCO percentage value obtained using POCOman software was 23.34 +/- 6.25 U, mean aggregate PCO severity grade was 0.46 +/- 0.28 U, and mean pixel-intensity value using ImageJ was 31.071 +/- 8.26 U. There was a significant positive correlation between the percentage PCO (P = 0.000; r = 0.864) and PCO severity grade (P = 0.001; r = 0.490) obtained for group 1 eyes using slit lamp retroillumination images and PCO pixel intensity obtained using Pentacam tomograms. CONCLUSIONS: Retroillumination photographs are the standard for quantifying PCO. Pentacam tomograms are easier to obtain and are free of flash reflections, and they allow for a more objective analysis. The correlation between the two methods demonstrates that ImageJ analysis of Pentacam tomograms is a viable tool for PCO analysis.

Duke Scholars

Published In

Invest Ophthalmol Vis Sci

DOI

ISSN

0146-0404

Publication Date

May 2008

Volume

49

Issue

5

Start / End Page

2004 / 2008

Location

United States

Related Subject Headings

  • Tomography
  • Reproducibility of Results
  • Photography
  • Ophthalmology & Optometry
  • Middle Aged
  • Lens Capsule, Crystalline
  • Image Processing, Computer-Assisted
  • Humans
  • Diagnostic Techniques, Ophthalmological
  • Cataract
 

Citation

APA
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ICMJE
MLA
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Grewal, D., Jain, R., Brar, G. S., & Grewal, S. P. S. (2008). Pentacam tomograms: a novel method for quantification of posterior capsule opacification. Invest Ophthalmol Vis Sci, 49(5), 2004–2008. https://doi.org/10.1167/iovs.07-1056
Grewal, Dilraj, Rajeev Jain, Gagandeep Singh Brar, and Satinder Pal Singh Grewal. “Pentacam tomograms: a novel method for quantification of posterior capsule opacification.Invest Ophthalmol Vis Sci 49, no. 5 (May 2008): 2004–8. https://doi.org/10.1167/iovs.07-1056.
Grewal D, Jain R, Brar GS, Grewal SPS. Pentacam tomograms: a novel method for quantification of posterior capsule opacification. Invest Ophthalmol Vis Sci. 2008 May;49(5):2004–8.
Grewal, Dilraj, et al. “Pentacam tomograms: a novel method for quantification of posterior capsule opacification.Invest Ophthalmol Vis Sci, vol. 49, no. 5, May 2008, pp. 2004–08. Pubmed, doi:10.1167/iovs.07-1056.
Grewal D, Jain R, Brar GS, Grewal SPS. Pentacam tomograms: a novel method for quantification of posterior capsule opacification. Invest Ophthalmol Vis Sci. 2008 May;49(5):2004–2008.

Published In

Invest Ophthalmol Vis Sci

DOI

ISSN

0146-0404

Publication Date

May 2008

Volume

49

Issue

5

Start / End Page

2004 / 2008

Location

United States

Related Subject Headings

  • Tomography
  • Reproducibility of Results
  • Photography
  • Ophthalmology & Optometry
  • Middle Aged
  • Lens Capsule, Crystalline
  • Image Processing, Computer-Assisted
  • Humans
  • Diagnostic Techniques, Ophthalmological
  • Cataract