Skip to main content
Journal cover image

Use of external ventriculostomy and intrathecal anti-fungal treatment in cerebral mucormycotic abscess.

Publication ,  Journal Article
Grannan, BL; Yanamadala, V; Venteicher, AS; Walcott, BP; Barr, JC
Published in: J Clin Neurosci
October 2014

Mucormycosis is an invasive fungal infection associated with a high mortality. Cerebral mucor abscesses can result secondary to rhinocerebral or hematogenous spread. Amphotericin B, posaconazole, and aggressive surgical resection are the hallmarks of treatment. While amphotericin is typically administered intravenously, less is known about the use of intrathecal amphotericin B. We describe a 42-year-old man who developed a cerebellar mucor abscess after undergoing hematopoietic stem cell transplant for the treatment of myelodysplastic syndrome. In the post-operative period he was admitted to the neurocritical care unit and received liposomal amphotericin B intravenously and through an external ventricular drain. This patient demonstrates that utilization of an external ventricular drain for intrathecal antifungal therapy in the post-operative period may warrant further study in patients with difficult to treat intracranial fungal abscesses.

Duke Scholars

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

October 2014

Volume

21

Issue

10

Start / End Page

1819 / 1821

Location

Scotland

Related Subject Headings

  • Ventriculostomy
  • Neurology & Neurosurgery
  • Myelodysplastic Syndromes
  • Mucormycosis
  • Male
  • Magnetic Resonance Angiography
  • Injections, Spinal
  • Humans
  • Hematopoietic Stem Cell Transplantation
  • Follow-Up Studies
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Grannan, B. L., Yanamadala, V., Venteicher, A. S., Walcott, B. P., & Barr, J. C. (2014). Use of external ventriculostomy and intrathecal anti-fungal treatment in cerebral mucormycotic abscess. J Clin Neurosci, 21(10), 1819–1821. https://doi.org/10.1016/j.jocn.2014.01.008
Grannan, Benjamin L., Vijay Yanamadala, Andrew S. Venteicher, Brian P. Walcott, and John C. Barr. “Use of external ventriculostomy and intrathecal anti-fungal treatment in cerebral mucormycotic abscess.J Clin Neurosci 21, no. 10 (October 2014): 1819–21. https://doi.org/10.1016/j.jocn.2014.01.008.
Grannan BL, Yanamadala V, Venteicher AS, Walcott BP, Barr JC. Use of external ventriculostomy and intrathecal anti-fungal treatment in cerebral mucormycotic abscess. J Clin Neurosci. 2014 Oct;21(10):1819–21.
Grannan, Benjamin L., et al. “Use of external ventriculostomy and intrathecal anti-fungal treatment in cerebral mucormycotic abscess.J Clin Neurosci, vol. 21, no. 10, Oct. 2014, pp. 1819–21. Pubmed, doi:10.1016/j.jocn.2014.01.008.
Grannan BL, Yanamadala V, Venteicher AS, Walcott BP, Barr JC. Use of external ventriculostomy and intrathecal anti-fungal treatment in cerebral mucormycotic abscess. J Clin Neurosci. 2014 Oct;21(10):1819–1821.
Journal cover image

Published In

J Clin Neurosci

DOI

EISSN

1532-2653

Publication Date

October 2014

Volume

21

Issue

10

Start / End Page

1819 / 1821

Location

Scotland

Related Subject Headings

  • Ventriculostomy
  • Neurology & Neurosurgery
  • Myelodysplastic Syndromes
  • Mucormycosis
  • Male
  • Magnetic Resonance Angiography
  • Injections, Spinal
  • Humans
  • Hematopoietic Stem Cell Transplantation
  • Follow-Up Studies