Thromboembolism after WATCHMANTM in a clopidogrel non-responder: A case for concern?
Publication
, Journal Article
Venkataraman, G; Bliden, KP; Tantry, US; Gurbel, PA
Published in: Catheter Cardiovasc Interv
July 2018
Atrial fibrillation (AF) is associated with an increased risk of stroke and thromboembolism (TE). The WATCHMANTM left atrial appendage (LAA) closure device is indicated to reduce the risk of TE from the LAA in patients with non-valvular AF. Here, we present a case of a patient with device-related thrombus who suffered a TE event two months after WATCHMANTM LAA closure and two weeks after switching from aspirin plus warfarin to aspirin plus clopidogrel therapy. Laboratory investigation identified the patient to be hypercoagulable and to be a non-responder to clopidogrel therapy. We discuss the potential role of platelet function testing to prevent device-related thrombi.
Duke Scholars
Published In
Catheter Cardiovasc Interv
DOI
EISSN
1522-726X
Publication Date
July 2018
Volume
92
Issue
1
Start / End Page
200 / 202
Location
United States
Related Subject Headings
- Warfarin
- Treatment Outcome
- Time Factors
- Thromboembolism
- Risk Factors
- Predictive Value of Tests
- Platelet Function Tests
- Platelet Aggregation Inhibitors
- Humans
- Female
Citation
APA
Chicago
ICMJE
MLA
NLM
Venkataraman, G., Bliden, K. P., Tantry, U. S., & Gurbel, P. A. (2018). Thromboembolism after WATCHMANTM in a clopidogrel non-responder: A case for concern? Catheter Cardiovasc Interv, 92(1), 200–202. https://doi.org/10.1002/ccd.27402
Venkataraman, Ganesh, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “Thromboembolism after WATCHMANTM in a clopidogrel non-responder: A case for concern?” Catheter Cardiovasc Interv 92, no. 1 (July 2018): 200–202. https://doi.org/10.1002/ccd.27402.
Venkataraman G, Bliden KP, Tantry US, Gurbel PA. Thromboembolism after WATCHMANTM in a clopidogrel non-responder: A case for concern? Catheter Cardiovasc Interv. 2018 Jul;92(1):200–2.
Venkataraman, Ganesh, et al. “Thromboembolism after WATCHMANTM in a clopidogrel non-responder: A case for concern?” Catheter Cardiovasc Interv, vol. 92, no. 1, July 2018, pp. 200–02. Pubmed, doi:10.1002/ccd.27402.
Venkataraman G, Bliden KP, Tantry US, Gurbel PA. Thromboembolism after WATCHMANTM in a clopidogrel non-responder: A case for concern? Catheter Cardiovasc Interv. 2018 Jul;92(1):200–202.
Published In
Catheter Cardiovasc Interv
DOI
EISSN
1522-726X
Publication Date
July 2018
Volume
92
Issue
1
Start / End Page
200 / 202
Location
United States
Related Subject Headings
- Warfarin
- Treatment Outcome
- Time Factors
- Thromboembolism
- Risk Factors
- Predictive Value of Tests
- Platelet Function Tests
- Platelet Aggregation Inhibitors
- Humans
- Female