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A novel role for renal epithelial cells and the medullary sodium gradient in the local immune response.

Publication ,  Journal Article
Wyatt, CM; Crowley, SD
Published in: Kidney Int
December 2017

The extreme hypertonicity of the renal medulla plays a central role in regulating volume status. A recent publication in Cell has identified a novel role for the high sodium environment and the local epithelial cells in the recruitment of mononuclear phagocytes, potentially contributing to the defense against ascending urinary tract infection.

Duke Scholars

Published In

Kidney Int

DOI

EISSN

1523-1755

Publication Date

December 2017

Volume

92

Issue

6

Start / End Page

1308 / 1311

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Urinary Tract Infections
  • Sodium
  • Kidney Medulla
  • Humans
  • Epithelial Cells
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Wyatt, C. M., & Crowley, S. D. (2017). A novel role for renal epithelial cells and the medullary sodium gradient in the local immune response. Kidney Int, 92(6), 1308–1311. https://doi.org/10.1016/j.kint.2017.10.005
Wyatt, Christina M., and Steven D. Crowley. “A novel role for renal epithelial cells and the medullary sodium gradient in the local immune response.Kidney Int 92, no. 6 (December 2017): 1308–11. https://doi.org/10.1016/j.kint.2017.10.005.
Wyatt, Christina M., and Steven D. Crowley. “A novel role for renal epithelial cells and the medullary sodium gradient in the local immune response.Kidney Int, vol. 92, no. 6, Dec. 2017, pp. 1308–11. Pubmed, doi:10.1016/j.kint.2017.10.005.
Journal cover image

Published In

Kidney Int

DOI

EISSN

1523-1755

Publication Date

December 2017

Volume

92

Issue

6

Start / End Page

1308 / 1311

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Urinary Tract Infections
  • Sodium
  • Kidney Medulla
  • Humans
  • Epithelial Cells
  • 3202 Clinical sciences
  • 1103 Clinical Sciences