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Stereocontrolled Synthesis of the Spiro Ketal Unit of Avermectin B1a Aglycon

Publication ,  Journal Article
Hanessian, S; Ugolini, A; Therien, M
Published in: Journal of Organic Chemistry
January 1, 1983
Published version (DOI)

A stereocontrolled total synthesis of the 1,7- dioxaspiro[5.5]undecene subunit of the avermectin Bla aglycon is presented based on the “chiron” approach which utilizes optically active starting materials. © 1983, American Chemical Society. All rights reserved.

Duke Scholars

Michael J. Therien
Author Michael J. Therien Chemistry
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Published In

Journal of Organic Chemistry

DOI

10.1021/jo00171a065

EISSN

1520-6904

ISSN

0022-3263

Publication Date

January 1, 1983

Volume

48

Issue

23

Start / End Page

4427 / 4430

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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MLA
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Hanessian, S., Ugolini, A., & Therien, M. (1983). Stereocontrolled Synthesis of the Spiro Ketal Unit of Avermectin B1a Aglycon. Journal of Organic Chemistry, 48(23), 4427–4430. https://doi.org/10.1021/jo00171a065
Hanessian, S., A. Ugolini, and M. Therien. “Stereocontrolled Synthesis of the Spiro Ketal Unit of Avermectin B1a Aglycon.” Journal of Organic Chemistry 48, no. 23 (January 1, 1983): 4427–30. https://doi.org/10.1021/jo00171a065.
Hanessian S, Ugolini A, Therien M. Stereocontrolled Synthesis of the Spiro Ketal Unit of Avermectin B1a Aglycon. Journal of Organic Chemistry. 1983 Jan 1;48(23):4427–30.
Hanessian, S., et al. “Stereocontrolled Synthesis of the Spiro Ketal Unit of Avermectin B1a Aglycon.” Journal of Organic Chemistry, vol. 48, no. 23, Jan. 1983, pp. 4427–30. Scopus, doi:10.1021/jo00171a065.
Hanessian S, Ugolini A, Therien M. Stereocontrolled Synthesis of the Spiro Ketal Unit of Avermectin B1a Aglycon. Journal of Organic Chemistry. 1983 Jan 1;48(23):4427–4430.
Journal cover image

Published In

Journal of Organic Chemistry

DOI

10.1021/jo00171a065

EISSN

1520-6904

ISSN

0022-3263

Publication Date

January 1, 1983

Volume

48

Issue

23

Start / End Page

4427 / 4430

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry