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Quality of life changes during the pre- to postdiagnosis period and treatment-related recovery time in older women with breast cancer.

Publication ,  Journal Article
Stover, AM; Mayer, DK; Muss, H; Wheeler, SB; Lyons, JC; Reeve, BB
Published in: Cancer
June 15, 2014

BACKGROUND: Health care providers have little population-based evidence about health-related quality of life (HRQOL) changes, from the pre- to postdiagnosis period, and treatment-related recovery time for women aged 65 years and older diagnosed with breast cancer. METHODS: Older women with and without breast cancer completed self-reports of HRQOL at baseline and 2 years later as part of annual Medicare Health Outcomes Surveys (MHOS). MHOS was linked to Surveillance, Epidemiology, and End Results registries, which were used to categorize women with breast cancer by treatment type (breast-conserving surgery, breast-conserving surgery plus radiation, mastectomy) and time since diagnosis at follow-up. Each cancer case diagnosed in 1998 through 2007 (N = 542) was matched to 5 women without cancer (N = 2710) using propensity score matching. Analysis of covariance models examined changes in HRQOL, adjusting for demographics and initial functioning. RESULTS: Older women within 6 months of diagnosis had greater declines than women without cancer in SF-36 Physical (-5.8 vs -1.8) and Mental (-3.6 vs -0.7) Component Summary scores, General Health (-12.3 vs -4.6), Vitality (-11.0 vs -2.2), Bodily Pain (-8.5 vs -2.1), Social Functioning (-15.1 vs -3.3), Role-Physical (-26.5 vs -3.9), and Role-Emotional (-13.1 vs -3.1) scores (all P < .05). By approximately 1 year, women with and without breast cancer had similar HRQOL. Comparable declines in Physical Component Summary and Role-Physical occurred across treatment types. CONCLUSIONS: Women aged 65 years and older diagnosed with breast cancer should be counseled that survivors within 6 months of diagnosis are vulnerable to HRQOL declines, compared to women without breast cancer, but that decrements generally wane after 12 months.

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Published In

Cancer

DOI

EISSN

1097-0142

Publication Date

June 15, 2014

Volume

120

Issue

12

Start / End Page

1881 / 1889

Location

United States

Related Subject Headings

  • Self Report
  • Quality of Life
  • Oncology & Carcinogenesis
  • Humans
  • Female
  • Cohort Studies
  • Breast Neoplasms
  • Aged, 80 and over
  • Aged
  • Age Factors
 

Citation

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Stover, A. M., Mayer, D. K., Muss, H., Wheeler, S. B., Lyons, J. C., & Reeve, B. B. (2014). Quality of life changes during the pre- to postdiagnosis period and treatment-related recovery time in older women with breast cancer. Cancer, 120(12), 1881–1889. https://doi.org/10.1002/cncr.28649
Stover, Angela M., Deborah K. Mayer, Hyman Muss, Stephanie B. Wheeler, Jessica C. Lyons, and Bryce B. Reeve. “Quality of life changes during the pre- to postdiagnosis period and treatment-related recovery time in older women with breast cancer.Cancer 120, no. 12 (June 15, 2014): 1881–89. https://doi.org/10.1002/cncr.28649.
Stover AM, Mayer DK, Muss H, Wheeler SB, Lyons JC, Reeve BB. Quality of life changes during the pre- to postdiagnosis period and treatment-related recovery time in older women with breast cancer. Cancer. 2014 Jun 15;120(12):1881–9.
Stover, Angela M., et al. “Quality of life changes during the pre- to postdiagnosis period and treatment-related recovery time in older women with breast cancer.Cancer, vol. 120, no. 12, June 2014, pp. 1881–89. Pubmed, doi:10.1002/cncr.28649.
Stover AM, Mayer DK, Muss H, Wheeler SB, Lyons JC, Reeve BB. Quality of life changes during the pre- to postdiagnosis period and treatment-related recovery time in older women with breast cancer. Cancer. 2014 Jun 15;120(12):1881–1889.
Journal cover image

Published In

Cancer

DOI

EISSN

1097-0142

Publication Date

June 15, 2014

Volume

120

Issue

12

Start / End Page

1881 / 1889

Location

United States

Related Subject Headings

  • Self Report
  • Quality of Life
  • Oncology & Carcinogenesis
  • Humans
  • Female
  • Cohort Studies
  • Breast Neoplasms
  • Aged, 80 and over
  • Aged
  • Age Factors