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Patient-reported outcomes assessment in cancer trials: taking stock, moving forward.

Publication ,  Conference
Lipscomb, J; Reeve, BB; Clauser, SB; Abrams, JS; Bruner, DW; Burke, LB; Denicoff, AM; Ganz, PA; Gondek, K; Minasian, LM; O'Mara, AM; Rock, EP ...
Published in: J Clin Oncol
November 10, 2007

To evaluate and improve the use of cancer trial end points that reflect the patient's own perspective, the National Cancer Institute organized an international conference, Patient-Reported Outcomes Assessment in Cancer Trials (PROACT), in 2006. The 13 preceding articles in this special issue of the Journal were commissioned in preparation for or in response to the PROACT conference, which was cosponsored by the American Cancer Society. Drawing from these articles and also commentary from the conference itself, this concluding report takes stock of what has been learned to date about the successes and challenges in patient-reported outcome (PRO) assessment in phase III, phase II, and symptom management trials in cancer and identifies ways to improve the scientific soundness, feasibility, and policy relevance of PROs in trials. Building on this synthesis of lessons learned, this article discusses specific administrative policies and management procedures to improve PRO data collection, analysis, and dissemination of findings; opportunities afforded by recent methodologic and technologic advances in PRO data collection and analysis to enhance the scientific soundness and cost efficiency of PRO use in trials; and the importance of better understanding the usefulness of PRO data to the full spectrum of cancer decision makers, including patients and families, health providers, public and private payers, regulatory agencies, and standards-setting organizations.

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Published In

J Clin Oncol

DOI

EISSN

1527-7755

Publication Date

November 10, 2007

Volume

25

Issue

32

Start / End Page

5133 / 5140

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Sickness Impact Profile
  • Quality of Life
  • Quality Indicators, Health Care
  • Patient Satisfaction
  • Oncology & Carcinogenesis
  • Neoplasms
  • Humans
  • Decision Making
  • Clinical Trials as Topic
 

Citation

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Lipscomb, J., Reeve, B. B., Clauser, S. B., Abrams, J. S., Bruner, D. W., Burke, L. B., … Trimble, E. L. (2007). Patient-reported outcomes assessment in cancer trials: taking stock, moving forward. In J Clin Oncol (Vol. 25, pp. 5133–5140). United States. https://doi.org/10.1200/JCO.2007.12.4644
Lipscomb, Joseph, Bryce B. Reeve, Steven B. Clauser, Jeffrey S. Abrams, Deborah Watkins Bruner, Laurie B. Burke, Andrea M. Denicoff, et al. “Patient-reported outcomes assessment in cancer trials: taking stock, moving forward.” In J Clin Oncol, 25:5133–40, 2007. https://doi.org/10.1200/JCO.2007.12.4644.
Lipscomb J, Reeve BB, Clauser SB, Abrams JS, Bruner DW, Burke LB, et al. Patient-reported outcomes assessment in cancer trials: taking stock, moving forward. In: J Clin Oncol. 2007. p. 5133–40.
Lipscomb, Joseph, et al. “Patient-reported outcomes assessment in cancer trials: taking stock, moving forward.J Clin Oncol, vol. 25, no. 32, 2007, pp. 5133–40. Pubmed, doi:10.1200/JCO.2007.12.4644.
Lipscomb J, Reeve BB, Clauser SB, Abrams JS, Bruner DW, Burke LB, Denicoff AM, Ganz PA, Gondek K, Minasian LM, O’Mara AM, Revicki DA, Rock EP, Rowland JH, Sgambati M, Trimble EL. Patient-reported outcomes assessment in cancer trials: taking stock, moving forward. J Clin Oncol. 2007. p. 5133–5140.

Published In

J Clin Oncol

DOI

EISSN

1527-7755

Publication Date

November 10, 2007

Volume

25

Issue

32

Start / End Page

5133 / 5140

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Sickness Impact Profile
  • Quality of Life
  • Quality Indicators, Health Care
  • Patient Satisfaction
  • Oncology & Carcinogenesis
  • Neoplasms
  • Humans
  • Decision Making
  • Clinical Trials as Topic