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Isocarboxazid. Efficacy and tolerance.

Publication ,  Journal Article
Davidson, J; Turnbull, C
Published in: J Affect Disord
May 1983

In a double-blind study, isocarboxazid was found to have greater efficacy than placebo. Patients with weight gain, increased appetite, and increased sleep responded particularly well, with a rapid onset of improvement that was apparent by one week. Their response to placebo was poor. Using a flexible dose, the modal range was 30-60 mg per day. Higher doses were poorly tolerated. At the doses used, side effects were generally mild, the most common being dizziness and myoclonus.

Duke Scholars

Published In

J Affect Disord

DOI

ISSN

0165-0327

Publication Date

May 1983

Volume

5

Issue

2

Start / End Page

183 / 189

Location

Netherlands

Related Subject Headings

  • Psychiatry
  • Male
  • Isocarboxazid
  • Humans
  • Female
  • Drug Tolerance
  • Double-Blind Method
  • Dose-Response Relationship, Drug
  • Depressive Disorder
  • 17 Psychology and Cognitive Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Davidson, J., & Turnbull, C. (1983). Isocarboxazid. Efficacy and tolerance. J Affect Disord, 5(2), 183–189. https://doi.org/10.1016/0165-0327(83)90012-5
Davidson, J., and C. Turnbull. “Isocarboxazid. Efficacy and tolerance.J Affect Disord 5, no. 2 (May 1983): 183–89. https://doi.org/10.1016/0165-0327(83)90012-5.
Davidson J, Turnbull C. Isocarboxazid. Efficacy and tolerance. J Affect Disord. 1983 May;5(2):183–9.
Davidson, J., and C. Turnbull. “Isocarboxazid. Efficacy and tolerance.J Affect Disord, vol. 5, no. 2, May 1983, pp. 183–89. Pubmed, doi:10.1016/0165-0327(83)90012-5.
Davidson J, Turnbull C. Isocarboxazid. Efficacy and tolerance. J Affect Disord. 1983 May;5(2):183–189.
Journal cover image

Published In

J Affect Disord

DOI

ISSN

0165-0327

Publication Date

May 1983

Volume

5

Issue

2

Start / End Page

183 / 189

Location

Netherlands

Related Subject Headings

  • Psychiatry
  • Male
  • Isocarboxazid
  • Humans
  • Female
  • Drug Tolerance
  • Double-Blind Method
  • Dose-Response Relationship, Drug
  • Depressive Disorder
  • 17 Psychology and Cognitive Sciences