Skip to main content

Site of mitomycin-C application during trabeculectomy

Publication ,  Journal Article
Prata, JA; Minckler, DS; Baerveldt, G; Lee, PP; Heuer, DK
Published in: Journal of Glaucoma
January 1, 1994

The outcome and postoperative complications after trabeculectomies with mitomycin-C application before flap dissection (episcleral) or after flap dissection (scleral bed) were analyzed retrospectively in 82 patients (82 eyes). Thirty-six eyes (43.9%) had an episcleral mitomycin-C application, and 46 (56.1%) had scleral-bed mitomycin-C administration. After a mean followup of 10.1 ± 3.8 months and 9.9 ± 4.3 months for the episcleral and scleral-bed groups, respectively, complete success (intraocular pressure ≤21 mm Hg without medications) was achieved in 18 eyes (50%) in the episcleral group and in 43 eyes (93.5%) in the scleral-bed group. Qualified success (intraocular pres-sure ≤21 mm Hg with glaucoma medications) was achieved in 10 eyes (27.8%) in the episcleral group and in 8 eyes (17.4%) in the scleral-bed group. Rates of cumulative survival and time of trabeculectomy survival were statistically higher in the scleral bed group (p = 0.002 and 0.0004, respectively). There was a statistically significant difference in the success rates between groups (p =0.03). The final intraocular pressure was significantly lower in the scleral-bed group (p = 0.015). There were no differences in duration of postoperative follow-up or frequency of complications. Mitomycin-C application after the scleral flap dissection appears to be associated with higher success rates than mitomycin-C application before scleral flap dissection. © 1994 Raven Press, Ltd.

Duke Scholars

Published In

Journal of Glaucoma

DOI

EISSN

1536-481X

ISSN

1057-0829

Publication Date

January 1, 1994

Volume

3

Issue

4

Start / End Page

296 / 301

Related Subject Headings

  • Ophthalmology & Optometry
  • 3212 Ophthalmology and optometry
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Prata, J. A., Minckler, D. S., Baerveldt, G., Lee, P. P., & Heuer, D. K. (1994). Site of mitomycin-C application during trabeculectomy. Journal of Glaucoma, 3(4), 296–301. https://doi.org/10.1097/00061198-199400340-00006
Prata, J. A., D. S. Minckler, G. Baerveldt, P. P. Lee, and D. K. Heuer. “Site of mitomycin-C application during trabeculectomy.” Journal of Glaucoma 3, no. 4 (January 1, 1994): 296–301. https://doi.org/10.1097/00061198-199400340-00006.
Prata JA, Minckler DS, Baerveldt G, Lee PP, Heuer DK. Site of mitomycin-C application during trabeculectomy. Journal of Glaucoma. 1994 Jan 1;3(4):296–301.
Prata, J. A., et al. “Site of mitomycin-C application during trabeculectomy.” Journal of Glaucoma, vol. 3, no. 4, Jan. 1994, pp. 296–301. Scopus, doi:10.1097/00061198-199400340-00006.
Prata JA, Minckler DS, Baerveldt G, Lee PP, Heuer DK. Site of mitomycin-C application during trabeculectomy. Journal of Glaucoma. 1994 Jan 1;3(4):296–301.

Published In

Journal of Glaucoma

DOI

EISSN

1536-481X

ISSN

1057-0829

Publication Date

January 1, 1994

Volume

3

Issue

4

Start / End Page

296 / 301

Related Subject Headings

  • Ophthalmology & Optometry
  • 3212 Ophthalmology and optometry
  • 1103 Clinical Sciences