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Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam.

Publication ,  Journal Article
Levintow, SN; Pence, BW; Ha, TV; Minh, NL; Sripaipan, T; Latkin, CA; Vu, PT; Quan, VM; Frangakis, C; Go, VF
Published in: PLoS One
2018

BACKGROUND: HIV infection is common among people who inject drugs (PWID), and HIV-positive PWID may be particularly vulnerable to depression. This study measured the prevalence of depressive symptoms and the factors associated with severe symptoms among 455 HIV-positive PWID in Thai Nguyen, Vietnam. METHODS: We used cross-sectional data from PWID in a randomized controlled trial of an intervention to reduce high-risk injecting and sexual behaviors in Thai Nguyen from 2009-2013. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale (CES-D). We used logistic regression to assess demographic, clinical, and psychosocial predictors of severe depressive symptoms (CES-D≥23) with prevalence odds ratios (POR) and 95% confidence intervals (CI). RESULTS: The prevalence of severe depressive symptoms (CES-D≥23) was 44%. 25% of participants had mild to moderate depressive symptoms (16≤CES-D<23), and 31% experienced no depressive symptoms (CES-D<16). Not being married, self-rated poor health, greater frequency of injection drug use, history of overdose, no alcohol use, and daily cigarette smoking were positively associated with severe depressive symptoms in unadjusted models and remained predictive in a multivariable model. The strongest predictors of depressive symptoms were self-reported poor health (POR = 2.94, 95% CI: 1.82, 4.76), no current alcohol use (POR = 2.35, 95% CI: 1.47, 3.77), and not currently married or cohabitating (POR = 2.21, 95% CI = 1.40, 3.47). CONCLUSION: Severe depressive symptoms were common among HIV-positive PWID in Thai Nguyen and were strongly associated with demographic, clinical, and psychosocial factors. Interventions that promote social support from family and reduce drug dependence may particularly benefit PWID experiencing severe depressive symptoms. Greater recognition and treatment of depressive symptoms has the potential to enhance quality of life and improve HIV clinical outcomes for PWID.

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Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2018

Volume

13

Issue

1

Start / End Page

e0191548

Location

United States

Related Subject Headings

  • Young Adult
  • Vietnam
  • Prevalence
  • Middle Aged
  • Male
  • Humans
  • HIV Infections
  • General Science & Technology
  • Depression
  • Adult
 

Citation

APA
Chicago
ICMJE
MLA
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Levintow, S. N., Pence, B. W., Ha, T. V., Minh, N. L., Sripaipan, T., Latkin, C. A., … Go, V. F. (2018). Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam. PLoS One, 13(1), e0191548. https://doi.org/10.1371/journal.pone.0191548
Levintow, Sara N., Brian W. Pence, Tran Viet Ha, Nguyen Le Minh, Teerada Sripaipan, Carl A. Latkin, Pham The Vu, Vu Minh Quan, Constantine Frangakis, and Vivian F. Go. “Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam.PLoS One 13, no. 1 (2018): e0191548. https://doi.org/10.1371/journal.pone.0191548.
Levintow SN, Pence BW, Ha TV, Minh NL, Sripaipan T, Latkin CA, et al. Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam. PLoS One. 2018;13(1):e0191548.
Levintow, Sara N., et al. “Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam.PLoS One, vol. 13, no. 1, 2018, p. e0191548. Pubmed, doi:10.1371/journal.pone.0191548.
Levintow SN, Pence BW, Ha TV, Minh NL, Sripaipan T, Latkin CA, Vu PT, Quan VM, Frangakis C, Go VF. Prevalence and predictors of depressive symptoms among HIV-positive men who inject drugs in Vietnam. PLoS One. 2018;13(1):e0191548.

Published In

PLoS One

DOI

EISSN

1932-6203

Publication Date

2018

Volume

13

Issue

1

Start / End Page

e0191548

Location

United States

Related Subject Headings

  • Young Adult
  • Vietnam
  • Prevalence
  • Middle Aged
  • Male
  • Humans
  • HIV Infections
  • General Science & Technology
  • Depression
  • Adult