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Masked Hypertension and Incident Clinic Hypertension Among Blacks in the Jackson Heart Study.

Publication ,  Journal Article
Abdalla, M; Booth, JN; Seals, SR; Spruill, TM; Viera, AJ; Diaz, KM; Sims, M; Muntner, P; Shimbo, D
Published in: Hypertension
July 2016

Masked hypertension, defined as nonelevated clinic blood pressure (BP) and elevated out-of-clinic BP may be an intermediary stage in the progression from normotension to hypertension. We examined the associations of out-of-clinic BP and masked hypertension using ambulatory BP monitoring with incident clinic hypertension in the Jackson Heart Study, a prospective cohort of blacks. Analyses included 317 participants with clinic BP <140/90 mm Hg, complete ambulatory BP monitoring, who were not taking antihypertensive medication at baseline in 2000 to 2004. Masked daytime hypertension was defined as mean daytime blood pressure ≥135/85 mm Hg, masked night-time hypertension as mean night-time BP ≥120/70 mm Hg, and masked 24-hour hypertension as mean 24-hour BP ≥130/80 mm Hg. Incident clinic hypertension, assessed at study visits in 2005 to 2008 and 2009 to 2012, was defined as the first visit with clinic systolic/diastolic BP ≥140/90 mm Hg or antihypertensive medication use. During a median follow-up of 8.1 years, there were 187 (59.0%) incident cases of clinic hypertension. Clinic hypertension developed in 79.2% and 42.2% of participants with and without any masked hypertension, 85.7% and 50.4% with and without masked daytime hypertension, 79.9% and 43.7% with and without masked night-time hypertension, and 85.7% and 48.2% with and without masked 24-hour hypertension, respectively. Multivariable-adjusted hazard ratios (95% confidence interval) of incident clinic hypertension for any masked hypertension and masked daytime, night-time, and 24-hour hypertension were 2.13 (1.51-3.02), 1.79 (1.24-2.60), 2.22 (1.58-3.12), and 1.91 (1.32-2.75), respectively. These findings suggest that ambulatory BP monitoring can identify blacks at increased risk for developing clinic hypertension.

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Published In

Hypertension

DOI

EISSN

1524-4563

Publication Date

July 2016

Volume

68

Issue

1

Start / End Page

220 / 226

Location

United States

Related Subject Headings

  • United States
  • Sex Distribution
  • Risk Assessment
  • Prospective Studies
  • Proportional Hazards Models
  • Prognosis
  • Middle Aged
  • Masked Hypertension
  • Male
  • Incidence
 

Citation

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Abdalla, M., Booth, J. N., Seals, S. R., Spruill, T. M., Viera, A. J., Diaz, K. M., … Shimbo, D. (2016). Masked Hypertension and Incident Clinic Hypertension Among Blacks in the Jackson Heart Study. Hypertension, 68(1), 220–226. https://doi.org/10.1161/HYPERTENSIONAHA.115.06904
Abdalla, Marwah, John N. Booth, Samantha R. Seals, Tanya M. Spruill, Anthony J. Viera, Keith M. Diaz, Mario Sims, Paul Muntner, and Daichi Shimbo. “Masked Hypertension and Incident Clinic Hypertension Among Blacks in the Jackson Heart Study.Hypertension 68, no. 1 (July 2016): 220–26. https://doi.org/10.1161/HYPERTENSIONAHA.115.06904.
Abdalla M, Booth JN, Seals SR, Spruill TM, Viera AJ, Diaz KM, et al. Masked Hypertension and Incident Clinic Hypertension Among Blacks in the Jackson Heart Study. Hypertension. 2016 Jul;68(1):220–6.
Abdalla, Marwah, et al. “Masked Hypertension and Incident Clinic Hypertension Among Blacks in the Jackson Heart Study.Hypertension, vol. 68, no. 1, July 2016, pp. 220–26. Pubmed, doi:10.1161/HYPERTENSIONAHA.115.06904.
Abdalla M, Booth JN, Seals SR, Spruill TM, Viera AJ, Diaz KM, Sims M, Muntner P, Shimbo D. Masked Hypertension and Incident Clinic Hypertension Among Blacks in the Jackson Heart Study. Hypertension. 2016 Jul;68(1):220–226.

Published In

Hypertension

DOI

EISSN

1524-4563

Publication Date

July 2016

Volume

68

Issue

1

Start / End Page

220 / 226

Location

United States

Related Subject Headings

  • United States
  • Sex Distribution
  • Risk Assessment
  • Prospective Studies
  • Proportional Hazards Models
  • Prognosis
  • Middle Aged
  • Masked Hypertension
  • Male
  • Incidence