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A convolutional neural network to filter artifacts in spectroscopic MRI.

Publication ,  Journal Article
Gurbani, SS; Schreibmann, E; Maudsley, AA; Cordova, JS; Soher, BJ; Poptani, H; Verma, G; Barker, PB; Shim, H; Cooper, LAD
Published in: Magn Reson Med
November 2018

PURPOSE: Proton MRSI is a noninvasive modality capable of generating volumetric maps of in vivo tissue metabolism without the need for ionizing radiation or injected contrast agent. Magnetic resonance spectroscopic imaging has been shown to be a viable imaging modality for studying several neuropathologies. However, a key hurdle in the routine clinical adoption of MRSI is the presence of spectral artifacts that can arise from a number of sources, possibly leading to false information. METHODS: A deep learning model was developed that was capable of identifying and filtering out poor quality spectra. The core of the model used a tiled convolutional neural network that analyzed frequency-domain spectra to detect artifacts. RESULTS: When compared with a panel of MRS experts, our convolutional neural network achieved high sensitivity and specificity with an area under the curve of 0.95. A visualization scheme was implemented to better understand how the convolutional neural network made its judgement on single-voxel or multivoxel MRSI, and the convolutional neural network was embedded into a pipeline capable of producing whole-brain spectroscopic MRI volumes in real time. CONCLUSION: The fully automated method for assessment of spectral quality provides a valuable tool to support clinical MRSI or spectroscopic MRI studies for use in fields such as adaptive radiation therapy planning.

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Published In

Magn Reson Med

DOI

EISSN

1522-2594

Publication Date

November 2018

Volume

80

Issue

5

Start / End Page

1765 / 1775

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • Deep Learning
  • Brain Neoplasms
  • Brain
  • Artifacts
  • Algorithms
  • 4003 Biomedical engineering
 

Citation

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Gurbani, S. S., Schreibmann, E., Maudsley, A. A., Cordova, J. S., Soher, B. J., Poptani, H., … Cooper, L. A. D. (2018). A convolutional neural network to filter artifacts in spectroscopic MRI. Magn Reson Med, 80(5), 1765–1775. https://doi.org/10.1002/mrm.27166
Gurbani, Saumya S., Eduard Schreibmann, Andrew A. Maudsley, James Scott Cordova, Brian J. Soher, Harish Poptani, Gaurav Verma, Peter B. Barker, Hyunsuk Shim, and Lee A. D. Cooper. “A convolutional neural network to filter artifacts in spectroscopic MRI.Magn Reson Med 80, no. 5 (November 2018): 1765–75. https://doi.org/10.1002/mrm.27166.
Gurbani SS, Schreibmann E, Maudsley AA, Cordova JS, Soher BJ, Poptani H, et al. A convolutional neural network to filter artifacts in spectroscopic MRI. Magn Reson Med. 2018 Nov;80(5):1765–75.
Gurbani, Saumya S., et al. “A convolutional neural network to filter artifacts in spectroscopic MRI.Magn Reson Med, vol. 80, no. 5, Nov. 2018, pp. 1765–75. Pubmed, doi:10.1002/mrm.27166.
Gurbani SS, Schreibmann E, Maudsley AA, Cordova JS, Soher BJ, Poptani H, Verma G, Barker PB, Shim H, Cooper LAD. A convolutional neural network to filter artifacts in spectroscopic MRI. Magn Reson Med. 2018 Nov;80(5):1765–1775.
Journal cover image

Published In

Magn Reson Med

DOI

EISSN

1522-2594

Publication Date

November 2018

Volume

80

Issue

5

Start / End Page

1765 / 1775

Location

United States

Related Subject Headings

  • Nuclear Medicine & Medical Imaging
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
  • Deep Learning
  • Brain Neoplasms
  • Brain
  • Artifacts
  • Algorithms
  • 4003 Biomedical engineering