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Report of a case combining solitary Peutz-Jeghers polyp, colitis cystica profunda, and high-grade dysplasia of the epithelium of the colon.

Publication ,  Journal Article
Papalampros, A; Vailas, MG; Sotiropoulou, M; Baili, E; Davakis, S; Moris, D; Felekouras, E; Deladetsima, I
Published in: World journal of surgical oncology
October 2017

Colitis cystica profunda is a rare nonneoplastic disease defined by the presence of intramural cysts that contain mucus, usually situated in the rectosigmoid area, which can mimic various malignant lesions and polyps. Its etiology still remains not fully elucidated, and several mechanisms such as congenital, post-traumatic, and infectious have been implicated in the development of this rare entity.Herein, we describe a unique case of colitis cystica profunda in the setting of Peutz-Jeghers-type polyp of the sigmoid colon, associated with high-grade dysplasia of the overlying epithelium in a 48-year-old female patient, who presented to the emergency room with signs of intestinal obstruction. To the best of our insight, this is the first manifestation ever reported in the literature regarding the coexistence of solitary Peutz-Jeghers-type polyp, colitis cystica profunda, and high-grade dysplasia of the epithelium of the colon.The purpose of this case report is to highlight colitis cystica profunda and its clinical significance. An uncommon nonneoplastic entity, many times masquerading as malignant lesion of the rectosigmoid area of the colon. Clinicians and pathologists should be aware of this benign condition that is found incidentally postoperatively in patients undergoing colectomies, leading to unnecessary increase of morbidity and mortality in these patients, who otherwise could have been cured with conservative treatment only.

Duke Scholars

Published In

World journal of surgical oncology

DOI

EISSN

1477-7819

ISSN

1477-7819

Publication Date

October 2017

Volume

15

Issue

1

Start / End Page

188

Related Subject Headings

  • Weight Loss
  • Tomography, X-Ray Computed
  • Peutz-Jeghers Syndrome
  • Oncology & Carcinogenesis
  • Middle Aged
  • Intestinal Mucosa
  • Humans
  • Gastrointestinal Hemorrhage
  • Female
  • Cysts
 

Citation

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Papalampros, A., Vailas, M. G., Sotiropoulou, M., Baili, E., Davakis, S., Moris, D., … Deladetsima, I. (2017). Report of a case combining solitary Peutz-Jeghers polyp, colitis cystica profunda, and high-grade dysplasia of the epithelium of the colon. World Journal of Surgical Oncology, 15(1), 188. https://doi.org/10.1186/s12957-017-1253-x
Papalampros, Alexandros, Michail G. Vailas, Maria Sotiropoulou, Efstratia Baili, Spiridon Davakis, Demetrios Moris, Evangelos Felekouras, and Ioanna Deladetsima. “Report of a case combining solitary Peutz-Jeghers polyp, colitis cystica profunda, and high-grade dysplasia of the epithelium of the colon.World Journal of Surgical Oncology 15, no. 1 (October 2017): 188. https://doi.org/10.1186/s12957-017-1253-x.
Papalampros A, Vailas MG, Sotiropoulou M, Baili E, Davakis S, Moris D, et al. Report of a case combining solitary Peutz-Jeghers polyp, colitis cystica profunda, and high-grade dysplasia of the epithelium of the colon. World journal of surgical oncology. 2017 Oct;15(1):188.
Papalampros, Alexandros, et al. “Report of a case combining solitary Peutz-Jeghers polyp, colitis cystica profunda, and high-grade dysplasia of the epithelium of the colon.World Journal of Surgical Oncology, vol. 15, no. 1, Oct. 2017, p. 188. Epmc, doi:10.1186/s12957-017-1253-x.
Papalampros A, Vailas MG, Sotiropoulou M, Baili E, Davakis S, Moris D, Felekouras E, Deladetsima I. Report of a case combining solitary Peutz-Jeghers polyp, colitis cystica profunda, and high-grade dysplasia of the epithelium of the colon. World journal of surgical oncology. 2017 Oct;15(1):188.
Journal cover image

Published In

World journal of surgical oncology

DOI

EISSN

1477-7819

ISSN

1477-7819

Publication Date

October 2017

Volume

15

Issue

1

Start / End Page

188

Related Subject Headings

  • Weight Loss
  • Tomography, X-Ray Computed
  • Peutz-Jeghers Syndrome
  • Oncology & Carcinogenesis
  • Middle Aged
  • Intestinal Mucosa
  • Humans
  • Gastrointestinal Hemorrhage
  • Female
  • Cysts