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A critical reappraisal of the treatment modalities of normal appearing thoracic aorta mural thrombi.

Publication ,  Journal Article
Karaolanis, G; Moris, D; Bakoyiannis, C; Tsilimigras, DI; Palla, V-V; Spartalis, E; Schizas, D; Georgopoulos, S
Published in: Annals of translational medicine
August 2017

Mural thrombus in non-atherosclerotic or aneurysmatic thoracic aorta is a relatively uncommon entity. Currently there is no consensus on the appropriate therapeutic algorithm of its management. We aim to present the current knowledge on the treatment of thoracic aorta mural thrombi (TAMT) in minimally atherosclerotic vessels and we hope that the juxtaposed discussions will shed light on the uncharted waters regarding this rare syndrome. The MEDLINE/PubMed database was searched for publications with the medical subject "aortic mural thrombus" and keywords "thoracic", "embolism", "normal vessel", "minimally atherosclerotic vessel" or "treatment". We restricted our search to English language, till January 2017. The electronic literature search yielded 23 reports that were deemed appropriate for further analysis. Anticoagulation is the standard of care for the treatment of the thrombus whereas surgical and interventional treatment seems to be related with increased mortality and lower recurrence rates. TAMT treatment is controversial. Anticoagulants are the mainstay of treatment but surgery seems to gain ground in several settings as an only therapy or a combined treatment modality. More data are needed on the role of novel oral anticoagulants and endografts.

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Published In

Annals of translational medicine

DOI

EISSN

2305-5847

ISSN

2305-5839

Publication Date

August 2017

Volume

5

Issue

15

Start / End Page

306

Related Subject Headings

  • 42 Health sciences
  • 32 Biomedical and clinical sciences
 

Citation

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Chicago
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MLA
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Karaolanis, G., Moris, D., Bakoyiannis, C., Tsilimigras, D. I., Palla, V.-V., Spartalis, E., … Georgopoulos, S. (2017). A critical reappraisal of the treatment modalities of normal appearing thoracic aorta mural thrombi. Annals of Translational Medicine, 5(15), 306. https://doi.org/10.21037/atm.2017.05.15
Karaolanis, Georgios, Demetrios Moris, Chris Bakoyiannis, Diamantis I. Tsilimigras, Viktoria-Varvara Palla, Eleftherios Spartalis, Dimitrios Schizas, and Sotirios Georgopoulos. “A critical reappraisal of the treatment modalities of normal appearing thoracic aorta mural thrombi.Annals of Translational Medicine 5, no. 15 (August 2017): 306. https://doi.org/10.21037/atm.2017.05.15.
Karaolanis G, Moris D, Bakoyiannis C, Tsilimigras DI, Palla V-V, Spartalis E, et al. A critical reappraisal of the treatment modalities of normal appearing thoracic aorta mural thrombi. Annals of translational medicine. 2017 Aug;5(15):306.
Karaolanis, Georgios, et al. “A critical reappraisal of the treatment modalities of normal appearing thoracic aorta mural thrombi.Annals of Translational Medicine, vol. 5, no. 15, Aug. 2017, p. 306. Epmc, doi:10.21037/atm.2017.05.15.
Karaolanis G, Moris D, Bakoyiannis C, Tsilimigras DI, Palla V-V, Spartalis E, Schizas D, Georgopoulos S. A critical reappraisal of the treatment modalities of normal appearing thoracic aorta mural thrombi. Annals of translational medicine. 2017 Aug;5(15):306.

Published In

Annals of translational medicine

DOI

EISSN

2305-5847

ISSN

2305-5839

Publication Date

August 2017

Volume

5

Issue

15

Start / End Page

306

Related Subject Headings

  • 42 Health sciences
  • 32 Biomedical and clinical sciences