Skip to main content

Asbestos Fiber Concentrations in the Lungs of Brake Repair Workers: An Updated Analysis Using Several Regression Methods to Handle Nondetectable Measurements.

Publication ,  Journal Article
Liu, Y; Marsh, GM; Roggli, VL
Published in: J Occup Environ Med
July 2018

OBJECTIVES: The aim of the study was to reanalyze an updated database of lung asbestos fiber levels for 21 brake repair workers who died of mesothelioma using robust maximum likelihood-based regression methods to address nondetectable measurements. METHODS: We applied bivariate normal regression to address the doubly left-censored situation where both the lung fiber concentration of noncommercial (TAA) and commercial amphiboles (AC) were subject to detection limits. For the single left-censored situation, we applied censored normal regression to study the relationship between duration of employment (DOE) and TAA. RESULTS: We found a statistically significant positive relationship between TAA and AC (β = 0.49, 95% confidence interval [CI], 0.11 to 0.86) and a not statistically significant relationship between DOE and TAA (β = 0.02, 95% CI, -0.03 to 0.06). CONCLUSIONS: Our results provide additional support for the conclusion that exposure to commercial amphibole asbestos, and not chrysotile, is related to the occurrence of mesothelioma among some brake workers.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Occup Environ Med

DOI

EISSN

1536-5948

Publication Date

July 2018

Volume

60

Issue

7

Start / End Page

661 / 671

Location

United States

Related Subject Headings

  • Regression Analysis
  • Pleural Neoplasms
  • Peritoneal Neoplasms
  • Occupational Exposure
  • Occupational Diseases
  • Middle Aged
  • Mesothelioma
  • Maintenance
  • Lung
  • Limit of Detection
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Liu, Y., Marsh, G. M., & Roggli, V. L. (2018). Asbestos Fiber Concentrations in the Lungs of Brake Repair Workers: An Updated Analysis Using Several Regression Methods to Handle Nondetectable Measurements. J Occup Environ Med, 60(7), 661–671. https://doi.org/10.1097/JOM.0000000000001320
Liu, Yimeng, Gary M. Marsh, and Victor L. Roggli. “Asbestos Fiber Concentrations in the Lungs of Brake Repair Workers: An Updated Analysis Using Several Regression Methods to Handle Nondetectable Measurements.J Occup Environ Med 60, no. 7 (July 2018): 661–71. https://doi.org/10.1097/JOM.0000000000001320.
Liu, Yimeng, et al. “Asbestos Fiber Concentrations in the Lungs of Brake Repair Workers: An Updated Analysis Using Several Regression Methods to Handle Nondetectable Measurements.J Occup Environ Med, vol. 60, no. 7, July 2018, pp. 661–71. Pubmed, doi:10.1097/JOM.0000000000001320.

Published In

J Occup Environ Med

DOI

EISSN

1536-5948

Publication Date

July 2018

Volume

60

Issue

7

Start / End Page

661 / 671

Location

United States

Related Subject Headings

  • Regression Analysis
  • Pleural Neoplasms
  • Peritoneal Neoplasms
  • Occupational Exposure
  • Occupational Diseases
  • Middle Aged
  • Mesothelioma
  • Maintenance
  • Lung
  • Limit of Detection