Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics
Publication
, Journal Article
Harrison, W; Pittman, P; Cummings, T
Published in: Saudi Journal of Ophthalmology
January 1, 2018
Pleomorphic adenoma (benign mixed tumor) is the most common epithelial neoplasm of the lacrimal gland. It is usually a slow growing, well-circumscribed, mass that is identical to its salivary gland counterpart. Patients generally have an excellent prognosis for vision and long-term survival after complete surgical excision. There is a tendency to reoccur, especially if there is an incomplete excision, and rarely, malignant transformation to carcinoma ex pleomorphic adenoma can occur, which has a much poorer prognosis. The molecular genetics of lacrimal gland pleomorphic adenomas have only recently been studies, but appear to display similar genetic aberration found in the salivary gland counterparts.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Saudi Journal of Ophthalmology
DOI
ISSN
1319-4534
Publication Date
January 1, 2018
Volume
32
Issue
1
Start / End Page
13 / 16
Citation
APA
Chicago
ICMJE
MLA
NLM
Harrison, W., Pittman, P., & Cummings, T. (2018). Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics. Saudi Journal of Ophthalmology, 32(1), 13–16. https://doi.org/10.1016/j.sjopt.2018.02.014
Harrison, W., P. Pittman, and T. Cummings. “Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics.” Saudi Journal of Ophthalmology 32, no. 1 (January 1, 2018): 13–16. https://doi.org/10.1016/j.sjopt.2018.02.014.
Harrison W, Pittman P, Cummings T. Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics. Saudi Journal of Ophthalmology. 2018 Jan 1;32(1):13–6.
Harrison, W., et al. “Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics.” Saudi Journal of Ophthalmology, vol. 32, no. 1, Jan. 2018, pp. 13–16. Scopus, doi:10.1016/j.sjopt.2018.02.014.
Harrison W, Pittman P, Cummings T. Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics. Saudi Journal of Ophthalmology. 2018 Jan 1;32(1):13–16.
Published In
Saudi Journal of Ophthalmology
DOI
ISSN
1319-4534
Publication Date
January 1, 2018
Volume
32
Issue
1
Start / End Page
13 / 16