Skip to main content

Epicardial adipose tissue and metabolic syndrome: An update protocol for systematic review and meta-analysis.

Publication ,  Journal Article
Roever, L; Resende, ES; Diniz, ALD; Penha-Silva, N; O'Connell, JL; Gomes, PFS; Zanetti, HR; Roerver-Borges, AS; Veloso, FC; Souza, FRD; Neto, M ...
Published in: Medicine (Baltimore)
April 2018

BACKGROUND: The prevalence of metabolic syndrome (MetS) and MetS-related stroke is set to increase dramatically in coming decades. MetS is a complex disease that includes endothelial dysfunction, insulin resistance, diabetes, hypertension, ectopic obesity, and dyslipidaemia, and an increased risk of cardiovascular events. However, there are no systematic analyses, or well-conducted meta-analyses to evaluate the relationship between epicardial adipose tissue (EAT) and (MetS). The aim of this study is to examine this association of EAT with MetS in different ages and sex. METHODS: The update systematic review, and meta-analysis will be conducted using published studies that will be identified from electronic databases (ie, PubMed, EMBASE, Web of Science, and Google Scholar. Studies that firstly, examined the association between EAT and MetS, secondly, focus on cohort, case-control, and cross-sectional studies, thirdly, were conducted among in adults aged between 40 and 70 years, fourth, provided sufficient data for calculating ORs or relative risk with a 95% CI, fifth, were published as original articles written in English or other languages, and sixth, have been published until January year 2018 will be included. Study selection, data collection, quality assessment, and statistical syntheses will be conducted based on discussions among investigators. RESULTS: Ethics approval was not required for this study because it was based on published studies. The results and findings of this study will be submitted and published in a scientific peer-reviewed journal. This study will provide a high quality synthesis on the association of EAT and MetS. CONCLUSION: This systematic review will provide evidence to assess whether there is a strong association of EAT and MetS, and its components.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Medicine (Baltimore)

DOI

EISSN

1536-5964

Publication Date

April 2018

Volume

97

Issue

16

Start / End Page

e0387

Location

United States

Related Subject Headings

  • Research Design
  • Pericardium
  • Metabolic Syndrome
  • Humans
  • Adipose Tissue
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Roever, L., Resende, E. S., Diniz, A. L. D., Penha-Silva, N., O’Connell, J. L., Gomes, P. F. S., … Brazilian Network of Research in Meta-analysis (BRAMETIS), . (2018). Epicardial adipose tissue and metabolic syndrome: An update protocol for systematic review and meta-analysis. Medicine (Baltimore), 97(16), e0387. https://doi.org/10.1097/MD.0000000000010387
Roever, Leonardo, Elmiro Santos Resende, Angélica Lemos Debs Diniz, Nilson Penha-Silva, João Lucas O’Connell, Paulo Fernando Silva Gomes, Hugo Ribeiro Zanetti, et al. “Epicardial adipose tissue and metabolic syndrome: An update protocol for systematic review and meta-analysis.Medicine (Baltimore) 97, no. 16 (April 2018): e0387. https://doi.org/10.1097/MD.0000000000010387.
Roever L, Resende ES, Diniz ALD, Penha-Silva N, O’Connell JL, Gomes PFS, et al. Epicardial adipose tissue and metabolic syndrome: An update protocol for systematic review and meta-analysis. Medicine (Baltimore). 2018 Apr;97(16):e0387.
Roever, Leonardo, et al. “Epicardial adipose tissue and metabolic syndrome: An update protocol for systematic review and meta-analysis.Medicine (Baltimore), vol. 97, no. 16, Apr. 2018, p. e0387. Pubmed, doi:10.1097/MD.0000000000010387.
Roever L, Resende ES, Diniz ALD, Penha-Silva N, O’Connell JL, Gomes PFS, Zanetti HR, Roerver-Borges AS, Veloso FC, Souza FRD, Duarte PRA, Fidale TM, Casella-Filho A, Dourado PMM, Chagas ACP, Ali-Hasan-Al-Saegh S, Reis PEO, Pinto RDMC, Oliveira GBF, Avezum Á, Neto M, Durães A, Silva RMFLD, Grande AJ, Denardi C, Lopes RD, Nerlekar N, Alizadeh S, Hernandez AV, Rosa MID, Biondi-Zoccai G, Brazilian Network of Research in Meta-analysis (BRAMETIS). Epicardial adipose tissue and metabolic syndrome: An update protocol for systematic review and meta-analysis. Medicine (Baltimore). 2018 Apr;97(16):e0387.

Published In

Medicine (Baltimore)

DOI

EISSN

1536-5964

Publication Date

April 2018

Volume

97

Issue

16

Start / End Page

e0387

Location

United States

Related Subject Headings

  • Research Design
  • Pericardium
  • Metabolic Syndrome
  • Humans
  • Adipose Tissue